In silico model-based exploration of the applicability of parallel artificial membrane permeability assay (PAMPA) to screen chemicals of environmental concern

Parallel Artificial Membrane Permeability Assay (PAMPA) is an in vitro laboratory method for screening the transmembrane permeability of chemicals. Stemming from medicinal chemistry, PAMPA has the potential for use in the cost-effective high-throughput evaluation of chemicals of environmental concer...

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Bibliographic Details
Main Authors: Shenghong Wang, Zhizhen Zhang, Dingsheng Li, Siena Elizabeth Illa, Li Li
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Environment International
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0160412022005165