Targeting of CD133+ Cancer Stem Cells by Mesenchymal Stem Cell Expressing TRAIL Reveals a Prospective Role of Apoptotic Gene Regulation in Non-Small Cell Lung Cancer

Targeting of CD133+ Cancer Stem Cells by Mesenchymal Stem Cell Expressing TRAIL Reveals a Prospective Role of Apoptotic Gene Regulation in Non-Small Cell Lung Cancer

Mesenchymal stem cells (MSCs) are emerging as vehicles for anti-tumor cytotherapy; however, investigation on its efficacy to target a specific cancer stem cell (CSC) population in non-small cell lung cancer (NSCLC) is lacking. Using assays to evaluate cell proliferation, apoptosis, and gene expressi...

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Bibliographic Details
Main Authors: Kamal Shaik Fakiruddin, Moon Nian Lim, Norshariza Nordin, Rozita Rosli, Zubaidah Zakaria, Syahril Abdullah
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cancers
Subjects:
mesenchymal stem cell
TRAIL
cytotherapy
apoptosis
cancer stem cells
non-small cell lung cancer
Online Access:https://www.mdpi.com/2072-6694/11/9/1261

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