True mineral digestibility in C57Bl/6J mice
Data on mineral digestibility is key to understand mineral homeostasis and refine the recommendations for the dietary intake of these nutrients. In farm animals and pets, there is plenty of data on mineral digestibility and influencing factors. In laboratory mice, however, there is a lack of informa...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2023-01-01
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| Series: | PLoS ONE |
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10431658/?tool=EBI |
| _version_ | 1797736852593049600 |
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| author | Linda F. Böswald Jasmin Wenderlein Wolfgang Siegert Reinhard K. Straubinger Ellen Kienzle |
| author_facet | Linda F. Böswald Jasmin Wenderlein Wolfgang Siegert Reinhard K. Straubinger Ellen Kienzle |
| author_sort | Linda F. Böswald |
| collection | DOAJ |
| description | Data on mineral digestibility is key to understand mineral homeostasis and refine the recommendations for the dietary intake of these nutrients. In farm animals and pets, there is plenty of data on mineral digestibility and influencing factors. In laboratory mice, however, there is a lack of information on mineral digestibility under maintenance conditions, although this should be the basis for studies on mineral homeostasis under experimental conditions. The aim of the present study was to analyse data on intake, faecal excretion, and apparent digestibility of calcium, phosphorus, sodium, potassium, and magnesium in C57BL/6J mice fed different maintenance diets with varying voluntary dry matter intake. Lucas-tests were used to quantify true digestibility and describe correlations between dietary intake and excretion/absorption of the nutrients. Calcium, phosphorus, and magnesium showed a linear correlation between intake and faecal excretion (R2: 0.77, 0.93 and 0.91, respectively). Intake and apparently digested amounts of sodium and potassium were correlated linearly (R2: 0.86 and 0.98, respectively). These data show that intake is the major determinant of absorption in the minerals listed above. Faecal calcium and phosphorus excretion were correlated as well (R2 = 0.75). |
| first_indexed | 2024-03-12T13:19:55Z |
| format | Article |
| id | doaj.art-ee2fae831d384470a69c3da88296188c |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-03-12T13:19:55Z |
| publishDate | 2023-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-ee2fae831d384470a69c3da88296188c2023-08-26T05:31:31ZengPublic Library of Science (PLoS)PLoS ONE1932-62032023-01-01188True mineral digestibility in C57Bl/6J miceLinda F. BöswaldJasmin WenderleinWolfgang SiegertReinhard K. StraubingerEllen KienzleData on mineral digestibility is key to understand mineral homeostasis and refine the recommendations for the dietary intake of these nutrients. In farm animals and pets, there is plenty of data on mineral digestibility and influencing factors. In laboratory mice, however, there is a lack of information on mineral digestibility under maintenance conditions, although this should be the basis for studies on mineral homeostasis under experimental conditions. The aim of the present study was to analyse data on intake, faecal excretion, and apparent digestibility of calcium, phosphorus, sodium, potassium, and magnesium in C57BL/6J mice fed different maintenance diets with varying voluntary dry matter intake. Lucas-tests were used to quantify true digestibility and describe correlations between dietary intake and excretion/absorption of the nutrients. Calcium, phosphorus, and magnesium showed a linear correlation between intake and faecal excretion (R2: 0.77, 0.93 and 0.91, respectively). Intake and apparently digested amounts of sodium and potassium were correlated linearly (R2: 0.86 and 0.98, respectively). These data show that intake is the major determinant of absorption in the minerals listed above. Faecal calcium and phosphorus excretion were correlated as well (R2 = 0.75).https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10431658/?tool=EBI |
| spellingShingle | Linda F. Böswald Jasmin Wenderlein Wolfgang Siegert Reinhard K. Straubinger Ellen Kienzle True mineral digestibility in C57Bl/6J mice PLoS ONE |
| title | True mineral digestibility in C57Bl/6J mice |
| title_full | True mineral digestibility in C57Bl/6J mice |
| title_fullStr | True mineral digestibility in C57Bl/6J mice |
| title_full_unstemmed | True mineral digestibility in C57Bl/6J mice |
| title_short | True mineral digestibility in C57Bl/6J mice |
| title_sort | true mineral digestibility in c57bl 6j mice |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10431658/?tool=EBI |
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