Neuraminidase in Virus-like Particles Contributes to the Protection against High Dose of Avian Influenza Virus Challenge Infection

Neuraminidase in Virus-like Particles Contributes to the Protection against High Dose of Avian Influenza Virus Challenge Infection

Neuraminidase is an important target for influenza vaccination. In this study, we generated avian influenza VLPs, expressing hemagglutinin (HA), neuraminidase (NA), HA and NA co-expressed (HANA), to evaluate the protective role of NA against a high (10LD<sub>50</sub>) and low (2LD<sub...

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Bibliographic Details
Main Authors: Hae-Ji Kang, Ki-Back Chu, Keon-Woong Yoon, Gi-Deok Eom, Jie Mao, Min-Ju Kim, Su-Hwa Lee, Eun-Kyung Moon, Fu-Shi Quan
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Pathogens
Subjects:
avian influenza
virus-like particle
neuraminidase
protection
Online Access:https://www.mdpi.com/2076-0817/10/10/1291

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