Candida albicans suppresses nitric oxide generation from macrophages via a secreted molecule.
Macrophages and neutrophils generate a potent burst of reactive oxygen and nitrogen species as a key aspect of the antimicrobial response. While most successful pathogens, including the fungus Candida albicans, encode enzymes for the detoxification of these compounds and repair of the resulting cell...
Main Authors: | John R Collette, Huaijin Zhou, Michael C Lorenz |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3995984?pdf=render |
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