Altered Lung Microbiome and Metabolome Profile in Children With Pulmonary Arterial Hypertension Associated With Congenital Heart Disease

Altered Lung Microbiome and Metabolome Profile in Children With Pulmonary Arterial Hypertension Associated With Congenital Heart Disease

BackgroundsPulmonary arterial hypertension (PAH) is characterized by progressive pulmonary vascular functional and structural changes, resulting in increased pulmonary vascular resistance and eventually right heart failure and death. Congenital Left-to-Right shunts (LTRS) is one type of congenital h...

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Bibliographic Details
Main Authors: Runwei Ma, Liming Cheng, Yi Song, Yi Sun, Wenting Gui, Yao Deng, Chao Xie, Min Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Medicine
Subjects:
pulmonary arterial hypertension
congenital heart disease
left to right shunt
lung
microbiome
metabolome
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.940784/full

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