A sustainable and efficient synthesis of benzyl phosphonates using PEG/KI catalytic system
An efficient and expedient protocol for the synthesis of benzyl phosphonates using KI/K2CO3 as a catalytic system and PEG-400 as benign solvent has been developed. The reaction proceeds smoothly at room temperature achieving excellent selectivity and yield of the corresponding products. The combinat...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2016-08-01
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| Series: | Frontiers in Chemistry |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fchem.2016.00035/full |
| _version_ | 1811268751132196864 |
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| author | Manoj B. Gawande Shamrao Disale Sandip Kale George Abraham Sandeep Kahandal Ashish Sawarkar |
| author_facet | Manoj B. Gawande Shamrao Disale Sandip Kale George Abraham Sandeep Kahandal Ashish Sawarkar |
| author_sort | Manoj B. Gawande |
| collection | DOAJ |
| description | An efficient and expedient protocol for the synthesis of benzyl phosphonates using KI/K2CO3 as a catalytic system and PEG-400 as benign solvent has been developed. The reaction proceeds smoothly at room temperature achieving excellent selectivity and yield of the corresponding products. The combination of PEG-400, KI and K2CO3 in this reaction avoids the need of volatile/toxic organic solvents and reactive alkali metals or metal nanoparticles/hydrides. We believe that this benign combination (PEG-400 and KI) could be used for other related organic transformations. |
| first_indexed | 2024-04-12T21:28:32Z |
| format | Article |
| id | doaj.art-ee37fa3bad0348b7bd5387a6fbb3b3b0 |
| institution | Directory Open Access Journal |
| issn | 2296-2646 |
| language | English |
| last_indexed | 2024-04-12T21:28:32Z |
| publishDate | 2016-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Chemistry |
| spelling | doaj.art-ee37fa3bad0348b7bd5387a6fbb3b3b02022-12-22T03:16:06ZengFrontiers Media S.A.Frontiers in Chemistry2296-26462016-08-01410.3389/fchem.2016.00035204089A sustainable and efficient synthesis of benzyl phosphonates using PEG/KI catalytic systemManoj B. Gawande0Shamrao Disale1Sandip Kale2George Abraham3Sandeep Kahandal4Ashish Sawarkar5Regional Centre of Advanced Technologies and Materials, Faculty of Science, Department of Physical Chemistry, Palacky University, Olomouc, Šlechtitelů 11, 783 71, Olomouc, Czech Republic.Department of Chemistry, Institute of Chemical Technology, Nathalal Parekh Marg, Matunga,Department of Chemistry, SIES College of Arts, Science and Commerce, Sion,Department of Chemistry, SIES College of Arts, Science and Commerce, Sion,Department of Chemistry, B. N. Bandodkar college of Science , ThaneDepartment of Chemical Engineering, Motilal Nehru National Institute of Technology, , Uttar Pradesh, India.An efficient and expedient protocol for the synthesis of benzyl phosphonates using KI/K2CO3 as a catalytic system and PEG-400 as benign solvent has been developed. The reaction proceeds smoothly at room temperature achieving excellent selectivity and yield of the corresponding products. The combination of PEG-400, KI and K2CO3 in this reaction avoids the need of volatile/toxic organic solvents and reactive alkali metals or metal nanoparticles/hydrides. We believe that this benign combination (PEG-400 and KI) could be used for other related organic transformations.http://journal.frontiersin.org/Journal/10.3389/fchem.2016.00035/fullsustainabilitygreen chemistryPEGKI +K2CO3synthesis of benzyl phosphonates. |
| spellingShingle | Manoj B. Gawande Shamrao Disale Sandip Kale George Abraham Sandeep Kahandal Ashish Sawarkar A sustainable and efficient synthesis of benzyl phosphonates using PEG/KI catalytic system Frontiers in Chemistry sustainability green chemistry PEG KI +K2CO3 synthesis of benzyl phosphonates. |
| title | A sustainable and efficient synthesis of benzyl phosphonates using PEG/KI catalytic system |
| title_full | A sustainable and efficient synthesis of benzyl phosphonates using PEG/KI catalytic system |
| title_fullStr | A sustainable and efficient synthesis of benzyl phosphonates using PEG/KI catalytic system |
| title_full_unstemmed | A sustainable and efficient synthesis of benzyl phosphonates using PEG/KI catalytic system |
| title_short | A sustainable and efficient synthesis of benzyl phosphonates using PEG/KI catalytic system |
| title_sort | sustainable and efficient synthesis of benzyl phosphonates using peg ki catalytic system |
| topic | sustainability green chemistry PEG KI +K2CO3 synthesis of benzyl phosphonates. |
| url | http://journal.frontiersin.org/Journal/10.3389/fchem.2016.00035/full |
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