Exosomal circHIPK3 derived from umbilical cord‐derived mesenchymal stem cells enhances skin fibroblast autophagy by blocking miR‐20b‐5p/ULK1/Atg13 axis

Exosomal circHIPK3 derived from umbilical cord‐derived mesenchymal stem cells enhances skin fibroblast autophagy by blocking miR‐20b‐5p/ULK1/Atg13 axis

ABSTRACT Background Umbilical cord‐derived mesenchymal stem cells (UCMSCs) could alleviate diabetes‐induced injury. Hence, this investigation aimed to explore the role and mechanism of UCMSCs‐derived exosomal circHIPK3 (exo‐circHIPK3) in diabetes mellitus (DM). Methods HFF‐1 cells were cultured in h...

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Bibliographic Details
Main Authors: Zhi‐Yang Qiu, Shi‐Shuai Lin, Nan‐Fang Pan, Zhi‐Hu Lin, Yun‐Chuan Pan, Zun‐Hong Liang
Format: Article
Language:English
Published: Wiley 2023-12-01
Series:Journal of Diabetes Investigation
Subjects:
autophagy
DM
Exo‐circHIPK3
Online Access:https://doi.org/10.1111/jdi.14077

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