CCR9 Expressing T Helper and T Follicular Helper Cells Exhibit Site-Specific Identities During Inflammatory Disease

CCR9 Expressing T Helper and T Follicular Helper Cells Exhibit Site-Specific Identities During Inflammatory Disease

CD4+ T helper (Th) cells that express the gut homing chemokine receptor CCR9 are increased in the peripheral blood of patients with inflammatory bowel disease and Sjögren's syndrome and in the inflamed lesions of autoimmune diseases that affect the accessory organs of the digestive system. Howe...

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Bibliographic Details
Main Authors: Ilaria Cosorich, Helen M. McGuire, Joanna Warren, Mark Danta, Cecile King
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Immunology
Subjects:
CCR9 C-C chemokine receptor type 9
T follicular helper
T helper
inflammation
GIT = gastrointestinal tract
autoimmunity
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02899/full

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