Nanohydrogels Based on Self-Assembly of Cationic Pullulan and Anionic Dextran Derivatives for Efficient Delivery of Piroxicam

Nanohydrogels Based on Self-Assembly of Cationic Pullulan and Anionic Dextran Derivatives for Efficient Delivery of Piroxicam

A cationic derivative of pullulan was obtained by grafting reaction and used together with dextran sulfate to form polysaccharide-based nanohydrogel cross-linked via electrostatic interactions between polyions. Due to the polycation-polyanion interactions nanohydrogel particles were formed instantly...

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Bibliographic Details
Main Authors: Dorota Lachowicz, Przemyslaw Mielczarek, Roma Wirecka, Katarzyna Berent, Anna Karewicz, Michał Szuwarzyński, Szczepan Zapotoczny
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Pharmaceutics
Subjects:
nanohydrogel
self-organization
piroxicam
cationic pullulan
anionic dextran
polyelectrolyte
Online Access:https://www.mdpi.com/1999-4923/11/12/622

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