The Most-Cited Articles on Retinoblastoma: A Fifty-Year Perspective

Purpose: To summarize the characteristics and trends of interest in retinoblastoma (Rb) in the last 50 years. Methods: The Web of Science Database was used to find all studies focused on Rb published from 1970 to 2018. The term “retinoblastoma” was used to search for the 100 most cited records. Resu...

Full description

Bibliographic Details
Main Authors: Rachel Shemesh, Hunter Sandler, Sarah Dichter, Ido Didi Fabian, Eedy Mezer, Tamara Wygnanski-Jaffe
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Vision
Subjects:
Online Access:https://www.mdpi.com/2411-5150/7/2/33
_version_ 1797592404731101184
author Rachel Shemesh
Hunter Sandler
Sarah Dichter
Ido Didi Fabian
Eedy Mezer
Tamara Wygnanski-Jaffe
author_facet Rachel Shemesh
Hunter Sandler
Sarah Dichter
Ido Didi Fabian
Eedy Mezer
Tamara Wygnanski-Jaffe
author_sort Rachel Shemesh
collection DOAJ
description Purpose: To summarize the characteristics and trends of interest in retinoblastoma (Rb) in the last 50 years. Methods: The Web of Science Database was used to find all studies focused on Rb published from 1970 to 2018. The term “retinoblastoma” was used to search for the 100 most cited records. Results: The mean number of citations was 153.55 ± 88.9. The majority were from the United States (US) (<i>n</i> = 68). Drs. Shields authored 38% of the papers. The number of citations per year was positively correlated with the number of authors, r = 0.26 (<i>p</i> = 0.008). The number of patients was significantly associated with the number of citations per year (<i>p</i> = 0.012). Although papers on radiotherapy were the most common, publications about intra-arterial chemotherapy (IAC) were associated with 88.3% more citations per year (<i>p</i> = 0.031) and papers on intravenous chemotherapy (IVC) were associated with 40.3% more citations per year (<i>p</i>= 0.04). Review and meta-analysis studies had a higher median of citations (10.5) than interventional (6.4) or observational (5.2) studies. Conclusions: This study compiles a comprehensive analysis of the most-cited articles on Rb. Studies with a higher number of citations per year were associated with IAC, which emphasizes the significance of the advances in Rb treatments that allow for the saving of eyes and vision as well as lives. Review studies had more citations than observational or interventional studies. More citations were associated with a larger number of authors or more reported patients per paper. These findings highlight the importance of collaborations to achieve relevant, high-quality research of Rb.
first_indexed 2024-03-11T01:50:33Z
format Article
id doaj.art-ee412e7d37124135ad6e9872d7fec26e
institution Directory Open Access Journal
issn 2411-5150
language English
last_indexed 2024-03-11T01:50:33Z
publishDate 2023-04-01
publisher MDPI AG
record_format Article
series Vision
spelling doaj.art-ee412e7d37124135ad6e9872d7fec26e2023-11-18T13:03:28ZengMDPI AGVision2411-51502023-04-01723310.3390/vision7020033The Most-Cited Articles on Retinoblastoma: A Fifty-Year PerspectiveRachel Shemesh0Hunter Sandler1Sarah Dichter2Ido Didi Fabian3Eedy Mezer4Tamara Wygnanski-Jaffe5Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv 6997801, IsraelSackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv 6997801, IsraelRuth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 3200003, IsraelSackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv 6997801, IsraelRuth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 3200003, IsraelSackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv 6997801, IsraelPurpose: To summarize the characteristics and trends of interest in retinoblastoma (Rb) in the last 50 years. Methods: The Web of Science Database was used to find all studies focused on Rb published from 1970 to 2018. The term “retinoblastoma” was used to search for the 100 most cited records. Results: The mean number of citations was 153.55 ± 88.9. The majority were from the United States (US) (<i>n</i> = 68). Drs. Shields authored 38% of the papers. The number of citations per year was positively correlated with the number of authors, r = 0.26 (<i>p</i> = 0.008). The number of patients was significantly associated with the number of citations per year (<i>p</i> = 0.012). Although papers on radiotherapy were the most common, publications about intra-arterial chemotherapy (IAC) were associated with 88.3% more citations per year (<i>p</i> = 0.031) and papers on intravenous chemotherapy (IVC) were associated with 40.3% more citations per year (<i>p</i>= 0.04). Review and meta-analysis studies had a higher median of citations (10.5) than interventional (6.4) or observational (5.2) studies. Conclusions: This study compiles a comprehensive analysis of the most-cited articles on Rb. Studies with a higher number of citations per year were associated with IAC, which emphasizes the significance of the advances in Rb treatments that allow for the saving of eyes and vision as well as lives. Review studies had more citations than observational or interventional studies. More citations were associated with a larger number of authors or more reported patients per paper. These findings highlight the importance of collaborations to achieve relevant, high-quality research of Rb.https://www.mdpi.com/2411-5150/7/2/33retinoblastomabibliometricscitationstreatmentchemotherapy
spellingShingle Rachel Shemesh
Hunter Sandler
Sarah Dichter
Ido Didi Fabian
Eedy Mezer
Tamara Wygnanski-Jaffe
The Most-Cited Articles on Retinoblastoma: A Fifty-Year Perspective
Vision
retinoblastoma
bibliometrics
citations
treatment
chemotherapy
title The Most-Cited Articles on Retinoblastoma: A Fifty-Year Perspective
title_full The Most-Cited Articles on Retinoblastoma: A Fifty-Year Perspective
title_fullStr The Most-Cited Articles on Retinoblastoma: A Fifty-Year Perspective
title_full_unstemmed The Most-Cited Articles on Retinoblastoma: A Fifty-Year Perspective
title_short The Most-Cited Articles on Retinoblastoma: A Fifty-Year Perspective
title_sort most cited articles on retinoblastoma a fifty year perspective
topic retinoblastoma
bibliometrics
citations
treatment
chemotherapy
url https://www.mdpi.com/2411-5150/7/2/33
work_keys_str_mv AT rachelshemesh themostcitedarticlesonretinoblastomaafiftyyearperspective
AT huntersandler themostcitedarticlesonretinoblastomaafiftyyearperspective
AT sarahdichter themostcitedarticlesonretinoblastomaafiftyyearperspective
AT idodidifabian themostcitedarticlesonretinoblastomaafiftyyearperspective
AT eedymezer themostcitedarticlesonretinoblastomaafiftyyearperspective
AT tamarawygnanskijaffe themostcitedarticlesonretinoblastomaafiftyyearperspective
AT rachelshemesh mostcitedarticlesonretinoblastomaafiftyyearperspective
AT huntersandler mostcitedarticlesonretinoblastomaafiftyyearperspective
AT sarahdichter mostcitedarticlesonretinoblastomaafiftyyearperspective
AT idodidifabian mostcitedarticlesonretinoblastomaafiftyyearperspective
AT eedymezer mostcitedarticlesonretinoblastomaafiftyyearperspective
AT tamarawygnanskijaffe mostcitedarticlesonretinoblastomaafiftyyearperspective