Analysis of 363 Genetic Variants in F5 via an Interactive Web Database Reveals New Insights into FV Deficiency and FV Leiden

Analysis of 363 Genetic Variants in F5 via an Interactive Web Database Reveals New Insights into FV Deficiency and FV Leiden

The inherited bleeding disorder Factor V (FV) deficiency and clotting risk factor FV Leiden are associated with genetic variants in the F5 gene. FV deficiency occurs with mild, moderate, severe, or asymptomatic phenotypes, and either dysfunctional or reduced amounts of plasma FV protein. Here we pre...

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Bibliographic Details
Main Authors: Christos Efthymiou, Emily H.T. Print, Anna Simmons, Stephen J. Perkins
Format: Article
Language:English
Published: Georg Thieme Verlag KG 2023-01-01
Series:TH Open
Subjects:
coagulation factors
protein structure
coagulation
gene mutations
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/a-1987-5978

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