A New Classification of the Severity of Psoriasis: What’s Moderate Psoriasis?
The purpose of this study is to propose a ranking system for the severity of psoriasis. The consensus method of selecting the indices to include and the classification of real patient profiles by an expert panel to create a gold standard of severity were used. The performance of potential cut-offs w...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-06-01
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| Series: | Life |
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| Online Access: | https://www.mdpi.com/2075-1729/11/7/627 |
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| author | Laura Salgado-Boquete José Manuel Carrascosa Mar Llamas-Velasco Ricardo Ruiz-Villaverde Pablo de la Cueva Isabel Belinchón |
| author_facet | Laura Salgado-Boquete José Manuel Carrascosa Mar Llamas-Velasco Ricardo Ruiz-Villaverde Pablo de la Cueva Isabel Belinchón |
| author_sort | Laura Salgado-Boquete |
| collection | DOAJ |
| description | The purpose of this study is to propose a ranking system for the severity of psoriasis. The consensus method of selecting the indices to include and the classification of real patient profiles by an expert panel to create a gold standard of severity were used. The performance of potential cut-offs was evaluated to create a ranking algorithm. The combined use of PASI, BSA, and sPGA may allow the classification of the severity of psoriatic patients. The final algorithm identifies severe patients in a single step (2 out 3 are met: PASI ≥ 11 or BSA ≥ 10 or sPGA ≥ 3), while two steps are required for mild ((2 out 3 are met: PASI ≤ 3 or BSA ≤ 5 or sPGA ≤ 2) and DLQI < 5) and moderate forms (the patient does not meet 2 out 3 (PASI ≥ 11 or BSA ≥ 10 or sPGA ≥ 3) but has a DLQI ≥ 5. A ranking algorithm is presented, consisting of different measures of disease which classifies psoriatic patients into three categories: mild, moderate, and severe. |
| first_indexed | 2024-03-10T09:59:12Z |
| format | Article |
| id | doaj.art-ee42ebb18c0040beab3dde6e0f6c9da0 |
| institution | Directory Open Access Journal |
| issn | 2075-1729 |
| language | English |
| last_indexed | 2024-03-10T09:59:12Z |
| publishDate | 2021-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Life |
| spelling | doaj.art-ee42ebb18c0040beab3dde6e0f6c9da02023-11-22T02:08:44ZengMDPI AGLife2075-17292021-06-0111762710.3390/life11070627A New Classification of the Severity of Psoriasis: What’s Moderate Psoriasis?Laura Salgado-Boquete0José Manuel Carrascosa1Mar Llamas-Velasco2Ricardo Ruiz-Villaverde3Pablo de la Cueva4Isabel Belinchón5Dermatology Department, Complejo Hospitalario Universitario de Pontevedra, 36003 Pontevedra, SpainDermatology Department, Hospital Universitari Germans Trias I Pujol, Universitat Autònoma de Barcelona, IGTP, 08916 Badalona, SpainDermatology Department, Hospital Universitario de La Princesa, 28006 Madrid, SpainDermatology Department, Hospital Universitario San Cecilio, Instituto Biosanitario de Granada, Ibs, 18016 Granada, SpainDermatology Department, Hospital Universitario Infanta Leonor, 28031 Madrid, SpainDermatology Department, Hospital General Universitario de Alicante-ISABIAL-UMH, 03010 Alicante, SpainThe purpose of this study is to propose a ranking system for the severity of psoriasis. The consensus method of selecting the indices to include and the classification of real patient profiles by an expert panel to create a gold standard of severity were used. The performance of potential cut-offs was evaluated to create a ranking algorithm. The combined use of PASI, BSA, and sPGA may allow the classification of the severity of psoriatic patients. The final algorithm identifies severe patients in a single step (2 out 3 are met: PASI ≥ 11 or BSA ≥ 10 or sPGA ≥ 3), while two steps are required for mild ((2 out 3 are met: PASI ≤ 3 or BSA ≤ 5 or sPGA ≤ 2) and DLQI < 5) and moderate forms (the patient does not meet 2 out 3 (PASI ≥ 11 or BSA ≥ 10 or sPGA ≥ 3) but has a DLQI ≥ 5. A ranking algorithm is presented, consisting of different measures of disease which classifies psoriatic patients into three categories: mild, moderate, and severe.https://www.mdpi.com/2075-1729/11/7/627psoriasisseverityclassificationmoderatediscriminationcut-offs |
| spellingShingle | Laura Salgado-Boquete José Manuel Carrascosa Mar Llamas-Velasco Ricardo Ruiz-Villaverde Pablo de la Cueva Isabel Belinchón A New Classification of the Severity of Psoriasis: What’s Moderate Psoriasis? Life psoriasis severity classification moderate discrimination cut-offs |
| title | A New Classification of the Severity of Psoriasis: What’s Moderate Psoriasis? |
| title_full | A New Classification of the Severity of Psoriasis: What’s Moderate Psoriasis? |
| title_fullStr | A New Classification of the Severity of Psoriasis: What’s Moderate Psoriasis? |
| title_full_unstemmed | A New Classification of the Severity of Psoriasis: What’s Moderate Psoriasis? |
| title_short | A New Classification of the Severity of Psoriasis: What’s Moderate Psoriasis? |
| title_sort | new classification of the severity of psoriasis what s moderate psoriasis |
| topic | psoriasis severity classification moderate discrimination cut-offs |
| url | https://www.mdpi.com/2075-1729/11/7/627 |
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