Localization and expression of two human b-defensins (HBD-1 and HBD-2) in intestinal biopsies of celiac patients
Innate immunity is the first line of defense against microorganisms in vertebrates and acts by providing an initial barrier to microorganisms and triggering adaptive immune responses (Ganz and Lehrer 1999; Oppenheim et al., 2002). Peptides such as b-defensins are an important component of this defen...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
PAGEPress Publications
2009-06-01
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| Series: | European Journal of Histochemistry |
| Online Access: | https://www.ejh.it/index.php/ejh/article/view/852 |
| _version_ | 1811280571324694528 |
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| author | M Boniotto D Pirulli MV Verga Falzacappa C Trevisiol T Gerarduzzi S Crovella |
| author_facet | M Boniotto D Pirulli MV Verga Falzacappa C Trevisiol T Gerarduzzi S Crovella |
| author_sort | M Boniotto |
| collection | DOAJ |
| description | Innate immunity is the first line of defense against microorganisms in vertebrates and acts by providing an initial barrier to microorganisms and triggering adaptive immune responses (Ganz and Lehrer 1999; Oppenheim et al., 2002). Peptides such as b-defensins are an important component of this defense, both providing a broad spectrum of antimicrobial activity against bacteria, fungi, mycobacteria and several enveloped viruses (Ganz and Leher, 1994) and showing chemotactic activity by linking and activating CCR6 (Hoover DM et al. , 2002). b-defensins are small cationic peptides that vary in their expression patterns and spectrum of pathogen specificity (Ganz and Leher, 2002). |
| first_indexed | 2024-04-13T01:17:08Z |
| format | Article |
| id | doaj.art-ee44dddc52ba48e7a1f037c53a12cf9d |
| institution | Directory Open Access Journal |
| issn | 1121-760X 2038-8306 |
| language | English |
| last_indexed | 2024-04-13T01:17:08Z |
| publishDate | 2009-06-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | European Journal of Histochemistry |
| spelling | doaj.art-ee44dddc52ba48e7a1f037c53a12cf9d2022-12-22T03:08:53ZengPAGEPress PublicationsEuropean Journal of Histochemistry1121-760X2038-83062009-06-0147410.4081/852586Localization and expression of two human b-defensins (HBD-1 and HBD-2) in intestinal biopsies of celiac patientsM BoniottoD PirulliMV Verga FalzacappaC TrevisiolT GerarduzziS CrovellaInnate immunity is the first line of defense against microorganisms in vertebrates and acts by providing an initial barrier to microorganisms and triggering adaptive immune responses (Ganz and Lehrer 1999; Oppenheim et al., 2002). Peptides such as b-defensins are an important component of this defense, both providing a broad spectrum of antimicrobial activity against bacteria, fungi, mycobacteria and several enveloped viruses (Ganz and Leher, 1994) and showing chemotactic activity by linking and activating CCR6 (Hoover DM et al. , 2002). b-defensins are small cationic peptides that vary in their expression patterns and spectrum of pathogen specificity (Ganz and Leher, 2002).https://www.ejh.it/index.php/ejh/article/view/852 |
| spellingShingle | M Boniotto D Pirulli MV Verga Falzacappa C Trevisiol T Gerarduzzi S Crovella Localization and expression of two human b-defensins (HBD-1 and HBD-2) in intestinal biopsies of celiac patients European Journal of Histochemistry |
| title | Localization and expression of two human b-defensins (HBD-1 and HBD-2) in intestinal biopsies of celiac patients |
| title_full | Localization and expression of two human b-defensins (HBD-1 and HBD-2) in intestinal biopsies of celiac patients |
| title_fullStr | Localization and expression of two human b-defensins (HBD-1 and HBD-2) in intestinal biopsies of celiac patients |
| title_full_unstemmed | Localization and expression of two human b-defensins (HBD-1 and HBD-2) in intestinal biopsies of celiac patients |
| title_short | Localization and expression of two human b-defensins (HBD-1 and HBD-2) in intestinal biopsies of celiac patients |
| title_sort | localization and expression of two human b defensins hbd 1 and hbd 2 in intestinal biopsies of celiac patients |
| url | https://www.ejh.it/index.php/ejh/article/view/852 |
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