Vaccinations and Healthy Ageing: How to Rise to the Challenge Following a Life-Course Vaccination Approach
In the context of an ageing population, one of the major Public Health goals is to promote healthy ageing. To rise to this challenge, rethinking conventional prevention paradigms and implementing them with vaccination at all stages of life is necessary. Indeed, vaccinations are able to both prevent...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-02-01
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| Series: | Vaccines |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-393X/10/3/375 |
| _version_ | 1797441251714269184 |
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| author | Francesca Scognamiglio Maria Pia Fantini Chiara Reno Marco Montalti Zeno Di Valerio Giorgia Soldà Aurelia Salussolia Giusy La Fauci Angelo Capodici Davide Gori |
| author_facet | Francesca Scognamiglio Maria Pia Fantini Chiara Reno Marco Montalti Zeno Di Valerio Giorgia Soldà Aurelia Salussolia Giusy La Fauci Angelo Capodici Davide Gori |
| author_sort | Francesca Scognamiglio |
| collection | DOAJ |
| description | In the context of an ageing population, one of the major Public Health goals is to promote healthy ageing. To rise to this challenge, rethinking conventional prevention paradigms and implementing them with vaccination at all stages of life is necessary. Indeed, vaccinations are able to both prevent pathogen specific diseases and all their downstream effects and to increase overall immune system plasticity and resilience. Our aim is to discuss the obstacles and opportunities in pursuing a “life-course vaccination approach” and to highlight the role of vaccines in healthy ageing. In doing so, we address the close connections between immunology and vaccinology advances and introduce the novel concept of immune fitness. Finally, we conclude that even though vaccinology is making giant steps towards tailored vaccination strategies, more studies are needed to investigate this topic. |
| first_indexed | 2024-03-09T12:20:21Z |
| format | Article |
| id | doaj.art-ee45554f166b46609561e49d8f5da68b |
| institution | Directory Open Access Journal |
| issn | 2076-393X |
| language | English |
| last_indexed | 2024-03-09T12:20:21Z |
| publishDate | 2022-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Vaccines |
| spelling | doaj.art-ee45554f166b46609561e49d8f5da68b2023-11-30T22:42:05ZengMDPI AGVaccines2076-393X2022-02-0110337510.3390/vaccines10030375Vaccinations and Healthy Ageing: How to Rise to the Challenge Following a Life-Course Vaccination ApproachFrancesca Scognamiglio0Maria Pia Fantini1Chiara Reno2Marco Montalti3Zeno Di Valerio4Giorgia Soldà5Aurelia Salussolia6Giusy La Fauci7Angelo Capodici8Davide Gori9School of Hygiene and Preventive Medicine, Department of Biomedical and Neuromotor Sciences, Public Health and Medical Statistics, University of Bologna, Via San Giacomo 12, 40126 Bologna, ItalyUnit of Hygiene, Department of Biomedical and Neuromotor Sciences, Public Health and Medical Statistics, University of Bologna, Via San Giacomo 12, 40126 Bologna, ItalySchool of Hygiene and Preventive Medicine, Department of Biomedical and Neuromotor Sciences, Public Health and Medical Statistics, University of Bologna, Via San Giacomo 12, 40126 Bologna, ItalySchool of Hygiene and Preventive Medicine, Department of Biomedical and Neuromotor Sciences, Public Health and Medical Statistics, University of Bologna, Via San Giacomo 12, 40126 Bologna, ItalySchool of Hygiene and Preventive Medicine, Department of Biomedical and Neuromotor Sciences, Public Health and Medical Statistics, University of Bologna, Via San Giacomo 12, 40126 Bologna, ItalySchool of Hygiene and Preventive Medicine, Department of Biomedical and Neuromotor Sciences, Public Health and Medical Statistics, University of Bologna, Via San Giacomo 12, 40126 Bologna, ItalySchool of Hygiene and Preventive Medicine, Department of Biomedical and Neuromotor Sciences, Public Health and Medical Statistics, University of Bologna, Via San Giacomo 12, 40126 Bologna, ItalySchool of Hygiene and Preventive Medicine, Department of Biomedical and Neuromotor Sciences, Public Health and Medical Statistics, University of Bologna, Via San Giacomo 12, 40126 Bologna, ItalySchool of Hygiene and Preventive Medicine, Department of Biomedical and Neuromotor Sciences, Public Health and Medical Statistics, University of Bologna, Via San Giacomo 12, 40126 Bologna, ItalyUnit of Hygiene, Department of Biomedical and Neuromotor Sciences, Public Health and Medical Statistics, University of Bologna, Via San Giacomo 12, 40126 Bologna, ItalyIn the context of an ageing population, one of the major Public Health goals is to promote healthy ageing. To rise to this challenge, rethinking conventional prevention paradigms and implementing them with vaccination at all stages of life is necessary. Indeed, vaccinations are able to both prevent pathogen specific diseases and all their downstream effects and to increase overall immune system plasticity and resilience. Our aim is to discuss the obstacles and opportunities in pursuing a “life-course vaccination approach” and to highlight the role of vaccines in healthy ageing. In doing so, we address the close connections between immunology and vaccinology advances and introduce the novel concept of immune fitness. Finally, we conclude that even though vaccinology is making giant steps towards tailored vaccination strategies, more studies are needed to investigate this topic.https://www.mdpi.com/2076-393X/10/3/375vaccinationhealthy ageingimmune fitnesslife-course vaccination |
| spellingShingle | Francesca Scognamiglio Maria Pia Fantini Chiara Reno Marco Montalti Zeno Di Valerio Giorgia Soldà Aurelia Salussolia Giusy La Fauci Angelo Capodici Davide Gori Vaccinations and Healthy Ageing: How to Rise to the Challenge Following a Life-Course Vaccination Approach Vaccines vaccination healthy ageing immune fitness life-course vaccination |
| title | Vaccinations and Healthy Ageing: How to Rise to the Challenge Following a Life-Course Vaccination Approach |
| title_full | Vaccinations and Healthy Ageing: How to Rise to the Challenge Following a Life-Course Vaccination Approach |
| title_fullStr | Vaccinations and Healthy Ageing: How to Rise to the Challenge Following a Life-Course Vaccination Approach |
| title_full_unstemmed | Vaccinations and Healthy Ageing: How to Rise to the Challenge Following a Life-Course Vaccination Approach |
| title_short | Vaccinations and Healthy Ageing: How to Rise to the Challenge Following a Life-Course Vaccination Approach |
| title_sort | vaccinations and healthy ageing how to rise to the challenge following a life course vaccination approach |
| topic | vaccination healthy ageing immune fitness life-course vaccination |
| url | https://www.mdpi.com/2076-393X/10/3/375 |
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