Neural connectivity moderators and mechanisms of ketamine treatment among treatment-resistant depressed patients: a randomized controlled trialResearch in context

Neural connectivity moderators and mechanisms of ketamine treatment among treatment-resistant depressed patients: a randomized controlled trialResearch in context

Summary: Background: Intravenous (IV) ketamine has emerged as a rapid and effective treatment for TRD. However, the specific neural mechanisms of ketamine's effects in humans remains unclear. Although neuroplasticity is implicated as a mechanism of action in animal models, relatively few rando...

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Bibliographic Details
Main Authors: Manivel Rengasamy, Sanjay Mathew, Robert Howland, Angela Griffo, Benjamin Panny, Rebecca Price
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:EBioMedicine
Subjects:
Ketamine
Neural connectivity
RCT
Resting-state
Positive mood induction
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396423004681

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