RETRACTED ARTICLE: Biosynthesis of Zn-doped CuFe2O4 nanoparticles and their cytotoxic activity
Abstract Zn-doped CuFe2O4 nanoparticles (NPs) were eco-friendly synthesized using plant extract. These nanoparticles were characterized by X-ray diffraction, Fourier-transform infrared spectroscopy, scanning electron microscope (SEM), energy-dispersive X-ray spectroscopy and thermal gravimetric anal...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2022-06-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-022-13692-2 |
| _version_ | 1797806812108423168 |
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| author | Maryam Darvish Navid Nasrabadi Farnoush Fotovat Setareh Khosravi Mehrdad Khatami Samira Jamali Elnaz Mousavi Siavash Iravani Abbas Rahdar |
| author_facet | Maryam Darvish Navid Nasrabadi Farnoush Fotovat Setareh Khosravi Mehrdad Khatami Samira Jamali Elnaz Mousavi Siavash Iravani Abbas Rahdar |
| author_sort | Maryam Darvish |
| collection | DOAJ |
| description | Abstract Zn-doped CuFe2O4 nanoparticles (NPs) were eco-friendly synthesized using plant extract. These nanoparticles were characterized by X-ray diffraction, Fourier-transform infrared spectroscopy, scanning electron microscope (SEM), energy-dispersive X-ray spectroscopy and thermal gravimetric analysis (TGA). SEM image showed spherical NPs with size range less than 30 nm. In the EDS diagram, the elements of zinc, copper, iron, and oxygen are shown. The cytotoxicity and anticancer properties of Zn-doped CuFe2O4 NPs were evaluated on macrophage normal cells and A549 lung cancer cells. The cytotoxic effects of Zn-doped CuFe2O4 and CuFe2O4 NPs on A549 cancer cell lines were analyzed. The Zn-doped CuFe2O4 and CuFe2O4 NPs demonstrated IC50 values 95.8 and 278.4 µg/mL on A549 cancer cell, respectively. Additionally, Zn-doped CuFe2O4 and CuFe2O4 NPs had IC80 values of 8.31 and 16.1 µg/mL on A549 cancer cell, respectively. Notably, doping Zn on CuFe2O4 NPs displayed better cytotoxic effects on A549 cancer cells compared with the CuFe2O4 NPs alone. Also spinel nanocrystals of Zn-doped CuFe2O4 (~ 13 nm) had a minimum toxicity (CC50 = 136.6 µg/mL) on macrophages J774 Cell Line. |
| first_indexed | 2024-03-13T06:13:02Z |
| format | Article |
| id | doaj.art-ee459337768841bc8cf25b8363b32947 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-03-13T06:13:02Z |
| publishDate | 2022-06-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-ee459337768841bc8cf25b8363b329472023-06-11T11:10:02ZengNature PortfolioScientific Reports2045-23222022-06-0112111110.1038/s41598-022-13692-2RETRACTED ARTICLE: Biosynthesis of Zn-doped CuFe2O4 nanoparticles and their cytotoxic activityMaryam Darvish0Navid Nasrabadi1Farnoush Fotovat2Setareh Khosravi3Mehrdad Khatami4Samira Jamali5Elnaz Mousavi6Siavash Iravani7Abbas Rahdar8Department of Endodontics, School of Dentistry, Kerman University of Medical SciencesDepartment of Endodontics, School of Dentistry, Birjand University of Medical SciencesDepartment of Prosthodontics, School of Dentistry, Hamadan University of Medical SciencesDepartment of Orthodontics, School of Dentistry, Alborz University of Medical SciencesDepartment of Medical Biotechnology, Faculty of Medical Sciences, Tarbiat Modares UniversityDepartment of Endodontics, Stomatological Hospital, College of Stomatology, Xi’an Jiaotong UniversityDental Sciences Research Center, Department of Endodontics, School of Dentistry, Guilan University of Medical SciencesFaculty of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical SciencesDepartment of Physics, University of ZabolAbstract Zn-doped CuFe2O4 nanoparticles (NPs) were eco-friendly synthesized using plant extract. These nanoparticles were characterized by X-ray diffraction, Fourier-transform infrared spectroscopy, scanning electron microscope (SEM), energy-dispersive X-ray spectroscopy and thermal gravimetric analysis (TGA). SEM image showed spherical NPs with size range less than 30 nm. In the EDS diagram, the elements of zinc, copper, iron, and oxygen are shown. The cytotoxicity and anticancer properties of Zn-doped CuFe2O4 NPs were evaluated on macrophage normal cells and A549 lung cancer cells. The cytotoxic effects of Zn-doped CuFe2O4 and CuFe2O4 NPs on A549 cancer cell lines were analyzed. The Zn-doped CuFe2O4 and CuFe2O4 NPs demonstrated IC50 values 95.8 and 278.4 µg/mL on A549 cancer cell, respectively. Additionally, Zn-doped CuFe2O4 and CuFe2O4 NPs had IC80 values of 8.31 and 16.1 µg/mL on A549 cancer cell, respectively. Notably, doping Zn on CuFe2O4 NPs displayed better cytotoxic effects on A549 cancer cells compared with the CuFe2O4 NPs alone. Also spinel nanocrystals of Zn-doped CuFe2O4 (~ 13 nm) had a minimum toxicity (CC50 = 136.6 µg/mL) on macrophages J774 Cell Line.https://doi.org/10.1038/s41598-022-13692-2 |
| spellingShingle | Maryam Darvish Navid Nasrabadi Farnoush Fotovat Setareh Khosravi Mehrdad Khatami Samira Jamali Elnaz Mousavi Siavash Iravani Abbas Rahdar RETRACTED ARTICLE: Biosynthesis of Zn-doped CuFe2O4 nanoparticles and their cytotoxic activity Scientific Reports |
| title | RETRACTED ARTICLE: Biosynthesis of Zn-doped CuFe2O4 nanoparticles and their cytotoxic activity |
| title_full | RETRACTED ARTICLE: Biosynthesis of Zn-doped CuFe2O4 nanoparticles and their cytotoxic activity |
| title_fullStr | RETRACTED ARTICLE: Biosynthesis of Zn-doped CuFe2O4 nanoparticles and their cytotoxic activity |
| title_full_unstemmed | RETRACTED ARTICLE: Biosynthesis of Zn-doped CuFe2O4 nanoparticles and their cytotoxic activity |
| title_short | RETRACTED ARTICLE: Biosynthesis of Zn-doped CuFe2O4 nanoparticles and their cytotoxic activity |
| title_sort | retracted article biosynthesis of zn doped cufe2o4 nanoparticles and their cytotoxic activity |
| url | https://doi.org/10.1038/s41598-022-13692-2 |
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