The landscape of coding RNA editing events in pediatric cancer

The landscape of coding RNA editing events in pediatric cancer

Abstract Background RNA editing leads to post-transcriptional variation in protein sequences and has important biological implications. We sought to elucidate the landscape of RNA editing events across pediatric cancers. Methods Using RNA-Seq data mapped by a pipeline designed to minimize mapping am...

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Bibliographic Details
Main Authors: Ji Wen, Michael Rusch, Samuel W. Brady, Ying Shao, Michael N. Edmonson, Timothy I. Shaw, Brent B. Powers, Liqing Tian, John Easton, Charles G. Mullighan, Tanja Gruber, David Ellison, Jinghui Zhang
Format: Article
Language:English
Published: BMC 2021-11-01
Series:BMC Cancer
Subjects:
RNA editing
Pediatric cancer
Genomics
Immunotherapy
Online Access:https://doi.org/10.1186/s12885-021-08956-5

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