Molecular Pathways of Carcinogenesis in Familial Adenomatous Polyposis

Molecular Pathways of Carcinogenesis in Familial Adenomatous Polyposis

Familial adenomatous polyposis (FAP) is a genetic syndrome characterized by the presence of multiple polyps in the gastrointestinal tract and a wide range of systemic extra-intestinal manifestations. Patients affected will inevitably undergo abdominal surgery due to the malignant transformation of o...

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Bibliographic Details
Main Authors: Ilaria Ditonno, Domenico Novielli, Francesca Celiberto, Salvatore Rizzi, Maria Rendina, Enzo Ierardi, Alfredo Di Leo, Giuseppe Losurdo
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:International Journal of Molecular Sciences
Subjects:
familial adenomatous polyposis
APC
cancerogenesis
microbiota
immune microenvironment
estrogen
Online Access:https://www.mdpi.com/1422-0067/24/6/5687

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