CLINICAL AND ELECTROENCEPHALOGRAPHIC SEMIOLOGY OF MYOCLONIC-ATONIC SEIZURES
Abstract: myoclonic-atonic seizures (MAS) – short epileptic generalized seizures in the form of sudden falling spells (or drop attacks). Inour study were vealed MAS in 1.3% of all cases of epilepsy with onset of seizures before 18 years old (n=1261). Predominance of man among the patients was reveal...
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| Format: | Article |
| Language: | Russian |
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IRBIS LLC
2016-05-01
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| Series: | Эпилепсия и пароксизмальные состояния |
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| Online Access: | https://www.epilepsia.su/jour/article/view/119 |
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| author | M. B. Mironov K. Yu. Mukhin T. M. Krasilschikova A. F. Dolinina A. S. Petrukhin |
| author_facet | M. B. Mironov K. Yu. Mukhin T. M. Krasilschikova A. F. Dolinina A. S. Petrukhin |
| author_sort | M. B. Mironov |
| collection | DOAJ |
| description | Abstract: myoclonic-atonic seizures (MAS) – short epileptic generalized seizures in the form of sudden falling spells (or drop attacks). Inour study were vealed MAS in 1.3% of all cases of epilepsy with onset of seizures before 18 years old (n=1261). Predominance of man among the patients was revealed (76.5% men versus 23.5% woman). The most often in the patients with MAS myoclonic-astatic epilepsy (MAE) was diagnosed – 41,2% of cases. Symptomatic and cryptogenic forms of focal epilepsy were diagnosed in 35.2% of the patients. Lennox-Gastaut syndrome was revealed in 23.6% of cases. Onset of epilepsy with MAS varied widely – from 9 month to 6 year soflife; middle age of onset was 3.4 years±1.28 years. In all the cases MAS occurred in combination with other types of seizures: there can be any of 9 differenttypes of seizures. The most often myoclonic seizures (70.6% of cases), generalized convulsive seizures (47.1%) and absences (47.1%) were registered. Remission was achieved in 64.7% cases of epilepsy, associated with MAS. Reduction of seizure frequency ≥50% on antiepileptic treatment was achieved in 29.4% of the patients. Only in one patient (5.9%) the therapy was not effective. Our study demonstrated different efficacyof antiepileptic drugs in the treatment of different epileptic syndromes, associated with MAS. |
| first_indexed | 2024-04-10T02:49:27Z |
| format | Article |
| id | doaj.art-ee46dba0187b45369988554a8f369a77 |
| institution | Directory Open Access Journal |
| issn | 2077-8333 2311-4088 |
| language | Russian |
| last_indexed | 2024-04-10T02:49:27Z |
| publishDate | 2016-05-01 |
| publisher | IRBIS LLC |
| record_format | Article |
| series | Эпилепсия и пароксизмальные состояния |
| spelling | doaj.art-ee46dba0187b45369988554a8f369a772023-03-13T07:44:14ZrusIRBIS LLCЭпилепсия и пароксизмальные состояния2077-83332311-40882016-05-01532433118CLINICAL AND ELECTROENCEPHALOGRAPHIC SEMIOLOGY OF MYOCLONIC-ATONIC SEIZURESM. B. Mironov0K. Yu. Mukhin1T. M. Krasilschikova2A. F. Dolinina3A. S. Petrukhin4Институт детской неврологии и эпилепсии имени Святителя Луки, МоскваИнститут детской неврологии и эпилепсии имени Святителя Луки, МоскваPirogov Russian National Research Medical University, MoscowОбластная клиническая детская больница, ЧелябинскPirogov Russian National Research Medical University, MoscowAbstract: myoclonic-atonic seizures (MAS) – short epileptic generalized seizures in the form of sudden falling spells (or drop attacks). Inour study were vealed MAS in 1.3% of all cases of epilepsy with onset of seizures before 18 years old (n=1261). Predominance of man among the patients was revealed (76.5% men versus 23.5% woman). The most often in the patients with MAS myoclonic-astatic epilepsy (MAE) was diagnosed – 41,2% of cases. Symptomatic and cryptogenic forms of focal epilepsy were diagnosed in 35.2% of the patients. Lennox-Gastaut syndrome was revealed in 23.6% of cases. Onset of epilepsy with MAS varied widely – from 9 month to 6 year soflife; middle age of onset was 3.4 years±1.28 years. In all the cases MAS occurred in combination with other types of seizures: there can be any of 9 differenttypes of seizures. The most often myoclonic seizures (70.6% of cases), generalized convulsive seizures (47.1%) and absences (47.1%) were registered. Remission was achieved in 64.7% cases of epilepsy, associated with MAS. Reduction of seizure frequency ≥50% on antiepileptic treatment was achieved in 29.4% of the patients. Only in one patient (5.9%) the therapy was not effective. Our study demonstrated different efficacyof antiepileptic drugs in the treatment of different epileptic syndromes, associated with MAS.https://www.epilepsia.su/jour/article/view/119myoclonic-atonic seizuresmyatonicmyoclonic-astaticdoose syndromemyoclonic-astatic epilepsysymptomatic epilepsysecondary bilateral synchrony |
| spellingShingle | M. B. Mironov K. Yu. Mukhin T. M. Krasilschikova A. F. Dolinina A. S. Petrukhin CLINICAL AND ELECTROENCEPHALOGRAPHIC SEMIOLOGY OF MYOCLONIC-ATONIC SEIZURES Эпилепсия и пароксизмальные состояния myoclonic-atonic seizures myatonic myoclonic-astatic doose syndrome myoclonic-astatic epilepsy symptomatic epilepsy secondary bilateral synchrony |
| title | CLINICAL AND ELECTROENCEPHALOGRAPHIC SEMIOLOGY OF MYOCLONIC-ATONIC SEIZURES |
| title_full | CLINICAL AND ELECTROENCEPHALOGRAPHIC SEMIOLOGY OF MYOCLONIC-ATONIC SEIZURES |
| title_fullStr | CLINICAL AND ELECTROENCEPHALOGRAPHIC SEMIOLOGY OF MYOCLONIC-ATONIC SEIZURES |
| title_full_unstemmed | CLINICAL AND ELECTROENCEPHALOGRAPHIC SEMIOLOGY OF MYOCLONIC-ATONIC SEIZURES |
| title_short | CLINICAL AND ELECTROENCEPHALOGRAPHIC SEMIOLOGY OF MYOCLONIC-ATONIC SEIZURES |
| title_sort | clinical and electroencephalographic semiology of myoclonic atonic seizures |
| topic | myoclonic-atonic seizures myatonic myoclonic-astatic doose syndrome myoclonic-astatic epilepsy symptomatic epilepsy secondary bilateral synchrony |
| url | https://www.epilepsia.su/jour/article/view/119 |
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