Solitary eosinophilic granuloma of the ulna: Diagnosis on fine needle aspiration cytology
Solitary eosinophilic granuloma is a part of the spectrum of Langerhans cell histiocytoses (LCH) which are rare diseases with varied clinical presentations. They comprise of three major overlapping syndromes: solitary eosinophilic granuloma (unifocal disease), Hand-Schueller-Christian disease (multi...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2008-01-01
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| Series: | Journal of Cytology |
| Subjects: | |
| Online Access: | http://www.jcytol.org/article.asp?issn=0970-9371;year=2008;volume=25;issue=4;spage=153;epage=156;aulast=Jain |
| _version_ | 1811251320196169728 |
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| author | Jain Anshu Alam Kiran Maheshwari Veena Jain Vivek Khan Roobina |
| author_facet | Jain Anshu Alam Kiran Maheshwari Veena Jain Vivek Khan Roobina |
| author_sort | Jain Anshu |
| collection | DOAJ |
| description | Solitary eosinophilic granuloma is a part of the spectrum of Langerhans cell histiocytoses (LCH) which are rare diseases with varied clinical presentations. They comprise of three major overlapping syndromes: solitary eosinophilic granuloma (unifocal disease), Hand-Schueller-Christian disease (multifocal, unisystem), and Letterer-Siwe disease (multifocal, multisystem). A case of solitary eosinophilic granuloma of the ulna is presented here for its relatively uncommon incidence and the difficulty in making an accurate diagnosis based on the radiological picture alone. We hereby, emphasize the importance of a quick and reliable diagnosis based on fine needle aspiration cytology, and the need to consider the possibility of LCH in the differential diagnoses of a slide showing a large number of histiocytes and eosinophils, as in tuberculosis, Hodgkin′s disease, and other primary and metastatic bony lesions. Characteristic nuclear grooves and a large number of eosinophils help in clinching the cytological diagnosis. |
| first_indexed | 2024-04-12T16:18:42Z |
| format | Article |
| id | doaj.art-ee4a7b9a91924dc6ba64cf2f321e8b9a |
| institution | Directory Open Access Journal |
| issn | 0970-9371 |
| language | English |
| last_indexed | 2024-04-12T16:18:42Z |
| publishDate | 2008-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Cytology |
| spelling | doaj.art-ee4a7b9a91924dc6ba64cf2f321e8b9a2022-12-22T03:25:39ZengWolters Kluwer Medknow PublicationsJournal of Cytology0970-93712008-01-01254153156Solitary eosinophilic granuloma of the ulna: Diagnosis on fine needle aspiration cytologyJain AnshuAlam KiranMaheshwari VeenaJain VivekKhan RoobinaSolitary eosinophilic granuloma is a part of the spectrum of Langerhans cell histiocytoses (LCH) which are rare diseases with varied clinical presentations. They comprise of three major overlapping syndromes: solitary eosinophilic granuloma (unifocal disease), Hand-Schueller-Christian disease (multifocal, unisystem), and Letterer-Siwe disease (multifocal, multisystem). A case of solitary eosinophilic granuloma of the ulna is presented here for its relatively uncommon incidence and the difficulty in making an accurate diagnosis based on the radiological picture alone. We hereby, emphasize the importance of a quick and reliable diagnosis based on fine needle aspiration cytology, and the need to consider the possibility of LCH in the differential diagnoses of a slide showing a large number of histiocytes and eosinophils, as in tuberculosis, Hodgkin′s disease, and other primary and metastatic bony lesions. Characteristic nuclear grooves and a large number of eosinophils help in clinching the cytological diagnosis.http://www.jcytol.org/article.asp?issn=0970-9371;year=2008;volume=25;issue=4;spage=153;epage=156;aulast=JainBone; FNAC; Langerhans cell histiocytosis; ulna. |
| spellingShingle | Jain Anshu Alam Kiran Maheshwari Veena Jain Vivek Khan Roobina Solitary eosinophilic granuloma of the ulna: Diagnosis on fine needle aspiration cytology Journal of Cytology Bone; FNAC; Langerhans cell histiocytosis; ulna. |
| title | Solitary eosinophilic granuloma of the ulna: Diagnosis on fine needle aspiration cytology |
| title_full | Solitary eosinophilic granuloma of the ulna: Diagnosis on fine needle aspiration cytology |
| title_fullStr | Solitary eosinophilic granuloma of the ulna: Diagnosis on fine needle aspiration cytology |
| title_full_unstemmed | Solitary eosinophilic granuloma of the ulna: Diagnosis on fine needle aspiration cytology |
| title_short | Solitary eosinophilic granuloma of the ulna: Diagnosis on fine needle aspiration cytology |
| title_sort | solitary eosinophilic granuloma of the ulna diagnosis on fine needle aspiration cytology |
| topic | Bone; FNAC; Langerhans cell histiocytosis; ulna. |
| url | http://www.jcytol.org/article.asp?issn=0970-9371;year=2008;volume=25;issue=4;spage=153;epage=156;aulast=Jain |
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