Single Cell Scale Neuronal and Glial Gene Expression and Putative Cell Phenotypes and Networks in the Nucleus Tractus Solitarius in an Alcohol Withdrawal Time Series

Single Cell Scale Neuronal and Glial Gene Expression and Putative Cell Phenotypes and Networks in the Nucleus Tractus Solitarius in an Alcohol Withdrawal Time Series

Alcohol withdrawal syndrome (AWS) is characterized by neuronal hyperexcitability, autonomic dysregulation, and severe negative emotion. The nucleus tractus solitarius (NTS) likely plays a prominent role in the neurological processes underlying these symptoms as it is the main viscerosensory nucleus...

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Bibliographic Details
Main Authors: Sean J. O’Sullivan, Damani McIntosh-Clarke, James Park, Rajanikanth Vadigepalli, James S. Schwaber
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Systems Neuroscience
Subjects:
alcohol withdrawal
neuroinflammation
RT-PCR
subphenotypes
single-cell heterogeneity
microglia
Online Access:https://www.frontiersin.org/articles/10.3389/fnsys.2021.739790/full

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