Treatment of schizophrenia and bipolar disorder (ChAD) - a review of the literature

Introduction and aims of the study: The aim of this study is to present recent reports on the treatment and therapy of schizophrenia and bipolar disorder (ChAD). The current treatment of patients affected by these diseases is difficult and unsatisfactory, therefore it is necessary to find new therap...

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Main Authors: Jakub Klas, Natalia Kluz, Mikołaj Makaryczew, Klaudia Piwowar
Format: Article
Language:English
Published: Kazimierz Wielki University 2021-09-01
Series:Journal of Education, Health and Sport
Subjects:
Online Access:https://apcz.umk.pl/JEHS/article/view/35398
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author Jakub Klas
Natalia Kluz
Mikołaj Makaryczew
Klaudia Piwowar
author_facet Jakub Klas
Natalia Kluz
Mikołaj Makaryczew
Klaudia Piwowar
author_sort Jakub Klas
collection DOAJ
description Introduction and aims of the study: The aim of this study is to present recent reports on the treatment and therapy of schizophrenia and bipolar disorder (ChAD). The current treatment of patients affected by these diseases is difficult and unsatisfactory, therefore it is necessary to find new therapeutic options that will improve the effectiveness of treatment For the purpose of this study, scientific papers were reviewed using the Google Scholar search engine covering studies from 2016 to 2021. A dozen papers covering the scope of the publication were selected. Results: In the treatment of schizophrenia, the use of cannabinoids is of greatest interest due to the action of the preparations on the endocannabinoid system. In the treatment of ChaD, promising reports have been published on the therapy with aripiprazole and the need to improve its use in the treatment of both akathisia and agitation. Furthermore, from the fact that abnormalities of calcium signalling are considered a possible pathophysiological process in ChAD, it has been suggested that calcium channel L antagonists may be potential therapeutic agents in bipolar affective disorder. One study also demonstrated the potential use of vortioxetine in the treatment of patients with a depressive episode. Conclusions: The results of recent studies on the treatment of schizophrenia and ChAD cited in this paper offer the prospect of creating treatment regimens that are more effective and targeted in the aforementioned diseases. However, further randomised trials are needed to confirm the effective use of the cited drugs in the treatment of these diseases.
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spelling doaj.art-ee50195d27c24c36a50dae5b6ba514ce2022-12-22T00:19:50ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062021-09-0111910.12775/JEHS.2021.11.09.061Treatment of schizophrenia and bipolar disorder (ChAD) - a review of the literatureJakub Klas0Natalia Kluz1Mikołaj Makaryczew2Klaudia Piwowar3Medical University of LublinMedical University of LublinMedical University of LublinMedical University of LublinIntroduction and aims of the study: The aim of this study is to present recent reports on the treatment and therapy of schizophrenia and bipolar disorder (ChAD). The current treatment of patients affected by these diseases is difficult and unsatisfactory, therefore it is necessary to find new therapeutic options that will improve the effectiveness of treatment For the purpose of this study, scientific papers were reviewed using the Google Scholar search engine covering studies from 2016 to 2021. A dozen papers covering the scope of the publication were selected. Results: In the treatment of schizophrenia, the use of cannabinoids is of greatest interest due to the action of the preparations on the endocannabinoid system. In the treatment of ChaD, promising reports have been published on the therapy with aripiprazole and the need to improve its use in the treatment of both akathisia and agitation. Furthermore, from the fact that abnormalities of calcium signalling are considered a possible pathophysiological process in ChAD, it has been suggested that calcium channel L antagonists may be potential therapeutic agents in bipolar affective disorder. One study also demonstrated the potential use of vortioxetine in the treatment of patients with a depressive episode. Conclusions: The results of recent studies on the treatment of schizophrenia and ChAD cited in this paper offer the prospect of creating treatment regimens that are more effective and targeted in the aforementioned diseases. However, further randomised trials are needed to confirm the effective use of the cited drugs in the treatment of these diseases. https://apcz.umk.pl/JEHS/article/view/35398schizophreniaChADbipolar disorder
spellingShingle Jakub Klas
Natalia Kluz
Mikołaj Makaryczew
Klaudia Piwowar
Treatment of schizophrenia and bipolar disorder (ChAD) - a review of the literature
Journal of Education, Health and Sport
schizophrenia
ChAD
bipolar disorder
title Treatment of schizophrenia and bipolar disorder (ChAD) - a review of the literature
title_full Treatment of schizophrenia and bipolar disorder (ChAD) - a review of the literature
title_fullStr Treatment of schizophrenia and bipolar disorder (ChAD) - a review of the literature
title_full_unstemmed Treatment of schizophrenia and bipolar disorder (ChAD) - a review of the literature
title_short Treatment of schizophrenia and bipolar disorder (ChAD) - a review of the literature
title_sort treatment of schizophrenia and bipolar disorder chad a review of the literature
topic schizophrenia
ChAD
bipolar disorder
url https://apcz.umk.pl/JEHS/article/view/35398
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AT klaudiapiwowar treatmentofschizophreniaandbipolardisorderchadareviewoftheliterature