Terpenes as bacterial efflux pump inhibitors: A systematic review

Terpenes as bacterial efflux pump inhibitors: A systematic review

Managing antibiotic resistance is a significant challenge in modern pharmacotherapy. While molecular analyses have identified efflux pump expression as an essential mechanism underlying multidrug resistance, the targeted drug development has occurred slower. Thus, considering the verification that t...

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Bibliographic Details
Main Authors: Kaio Jefté Santos De Oliveira Dias, Gustavo Marinho Miranda, Jonatas Reis Bessa, Ana Carolina Justino De Araújo, Priscilla Ramos Freitas, Ray Silva De Almeida, Cícera Laura Roque Paulo, José Bezerra De Araújo Neto, Henrique D. M. Coutinho, Jaime Ribeiro-Filho
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Pharmacology
Subjects:
terpenes
efflux pumps
antibiotic resistance
natural products
systematic review
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.953982/full

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