Metabolomic Study of Biochemical Changes Related to Toxicity Induced by Bupleurotoxin Using LC-MS Coupled with a Pattern Recognition Approach

Metabolomic Study of Biochemical Changes Related to Toxicity Induced by Bupleurotoxin Using LC-MS Coupled with a Pattern Recognition Approach

The purpose of this study was to detect changes in urine of mice and to clarify the toxicity induced by bupleurotoxin (BETX) using liquid chromatography/quadrupole time-of-flight mass spectrometry (LC-Q-TOF-MS). A procedure for urine analysis using pattern recognition was proposed to evaluate the to...

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Bibliographic Details
Main Authors:	Zhong-Xiao Zhang, Juan Su, Xin-Ru Liu, Wei-Xing Dai, Shi-Kai Yan, Wei-Dong Zhang
Format:	Article
Language:	English
Published:	Wolters Kluwer Medknow Publications 2015-01-01
Series:	World Journal of Traditional Chinese Medicine
Subjects:	bupleurotoxin metabolomic profiling toxicity biomarker LC-Q-TOF-MS
Online Access:	http://www.wjtcm.org:8080/ch/reader/create_pdf.aspx?file_no=20140008&year_id=2015&quarter_id=1&flag=1

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