Evidence for the extracellular delivery of influenza NS1 protein
We constructed a reporter influenza A/Puerto Rico/8/1934 virus expressing truncated 124aa N-terminal NS1 protein fused to a luciferase reporter sequence (NanoLuc) without signal peptide. The reproduction activity of the vector correlated well with the luminescent activity in the lysates of infected...
Main Authors: | Anastasia A. Pulkina, Maria V. Sergeeva, Artem Krokhin, Marina A. Stukova, Andrej Egorov |
---|---|
Format: | Article |
Language: | English |
Published: |
Doctrine
2021-06-01
|
Series: | Microbiology Independent Research Journal |
Online Access: | https://www.scienceopen.com/hosted-document?doi=10.18527/2500-2236-2021-8-1-27-37 |
Similar Items
-
Intranasal Immunization with the Influenza A Virus Encoding Truncated NS1 Protein Protects Mice from Heterologous Challenge by Restraining the Inflammatory Response in the Lungs
by: Kirill Vasilyev, et al.
Published: (2021-03-01) -
Enhancement of the immunogenicity of influenza A virus by the inhibition of immunosuppressive function of NS1 protein
by: Kirill A. Vasilyev, et al.
Published: (2018-10-01) -
Enhanced CD8 + T-cell response in mice immunized with NS1-truncated influenza virus
by: Kirill A. Vasilyev, et al.
Published: (2020-02-01) -
IgGκ Signal Peptide Enhances the Efficacy of an Influenza Vector Vaccine against Respiratory Syncytial Virus Infection in Mice
by: Anastasia Pulkina, et al.
Published: (2023-07-01) -
Changes in RNA secondary structure affect NS1 protein expression during early stage influenza virus infection
by: Irina Baranovskaya, et al.
Published: (2019-12-01)