Potent neutralizing antibodies in humans infected with zoonotic simian foamy viruses target conserved epitopes located in the dimorphic domain of the surface envelope protein.

Potent neutralizing antibodies in humans infected with zoonotic simian foamy viruses target conserved epitopes located in the dimorphic domain of the surface envelope protein.

Human diseases of zoonotic origin are a major public health problem. Simian foamy viruses (SFVs) are complex retroviruses which are currently spilling over to humans. Replication-competent SFVs persist over the lifetime of their human hosts, without spreading to secondary hosts, suggesting the prese...

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Bibliographic Details
Main Authors: Caroline Lambert, Mathilde Couteaudier, Julie Gouzil, Léa Richard, Thomas Montange, Edouard Betsem, Réjane Rua, Joelle Tobaly-Tapiero, Dirk Lindemann, Richard Njouom, Augustin Mouinga-Ondémé, Antoine Gessain, Florence Buseyne
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-10-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC6193739?pdf=render

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