Bis-Schiff Bases of Isatin Derivatives Synthesis, and their Biological Activities: A Review
Isatin is a heterocyclic molecule that belongs to one of the most important classes of organic compounds known as indolines. Isatin, isatin analogs, and their Schiff bases have recently attracted a lot of attention in medicinal chemistry. Isatin, itself, shows various biological activities such as...
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| Format: | Article |
| Language: | English |
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College of Pharmacy / Mustansiriyah University
2022-07-01
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| Series: | Al-Mustansiriyah Journal of Pharmaceutical Sciences |
| Subjects: | |
| Online Access: | https://ajps.uomustansiriyah.edu.iq/index.php/AJPS/article/view/827 |
| _version_ | 1827293829080809472 |
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| author | May Mohammed Jawad Al-Mudhafar Tagreed N-A Omar Shayma L. Abdulhadi |
| author_facet | May Mohammed Jawad Al-Mudhafar Tagreed N-A Omar Shayma L. Abdulhadi |
| author_sort | May Mohammed Jawad Al-Mudhafar |
| collection | DOAJ |
| description |
Isatin is a heterocyclic molecule that belongs to one of the most important classes of organic compounds known as indolines. Isatin, isatin analogs, and their Schiff bases have recently attracted a lot of attention in medicinal chemistry. Isatin, itself, shows various biological activities such as antiviral, anticancer, antimicrobial, anti-inflammatory, analgesic, antioxidant, and anticonvulsant. Bis- Schiff bases containing isatin moiety have been known to possess a wide spectrum of pharmacological activities. This review offers up-to-date information on the most active isatin bis-Schiff bases, which would include anticancer, antimicrobial, antiviral, anticonvulsant, anti-inflammatory, and analgesic activities. These observations can lead to new molecular modifications that result in compounds with more desirable pharmacological properties
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| first_indexed | 2024-04-24T13:45:36Z |
| format | Article |
| id | doaj.art-ee59e9e049e54c4ba0a2f297ab090ed6 |
| institution | Directory Open Access Journal |
| issn | 1815-0993 2959-183X |
| language | English |
| last_indexed | 2024-04-24T13:45:36Z |
| publishDate | 2022-07-01 |
| publisher | College of Pharmacy / Mustansiriyah University |
| record_format | Article |
| series | Al-Mustansiriyah Journal of Pharmaceutical Sciences |
| spelling | doaj.art-ee59e9e049e54c4ba0a2f297ab090ed62024-04-04T06:56:26ZengCollege of Pharmacy / Mustansiriyah UniversityAl-Mustansiriyah Journal of Pharmaceutical Sciences1815-09932959-183X2022-07-0122110.32947/ajps.v22i1.827Bis-Schiff Bases of Isatin Derivatives Synthesis, and their Biological Activities: A ReviewMay Mohammed Jawad Al-Mudhafar0Tagreed N-A Omar1Shayma L. Abdulhadi2*Department of Pharmaceutical Chemistry, College of Pharmacy, University of Baghdad Bab Al-Moadham*Department of Pharmaceutical Chemistry, College of Pharmacy, University of Baghdad Bab Al-Moadham*Department of Pharmaceutical Chemistry, College of Pharmacy, University of Baghdad Bab Al-Moadham Isatin is a heterocyclic molecule that belongs to one of the most important classes of organic compounds known as indolines. Isatin, isatin analogs, and their Schiff bases have recently attracted a lot of attention in medicinal chemistry. Isatin, itself, shows various biological activities such as antiviral, anticancer, antimicrobial, anti-inflammatory, analgesic, antioxidant, and anticonvulsant. Bis- Schiff bases containing isatin moiety have been known to possess a wide spectrum of pharmacological activities. This review offers up-to-date information on the most active isatin bis-Schiff bases, which would include anticancer, antimicrobial, antiviral, anticonvulsant, anti-inflammatory, and analgesic activities. These observations can lead to new molecular modifications that result in compounds with more desirable pharmacological properties https://ajps.uomustansiriyah.edu.iq/index.php/AJPS/article/view/827: Isatin, Isatin Bis-Schiff bases, biological activities. |
| spellingShingle | May Mohammed Jawad Al-Mudhafar Tagreed N-A Omar Shayma L. Abdulhadi Bis-Schiff Bases of Isatin Derivatives Synthesis, and their Biological Activities: A Review Al-Mustansiriyah Journal of Pharmaceutical Sciences : Isatin, Isatin Bis-Schiff bases, biological activities. |
| title | Bis-Schiff Bases of Isatin Derivatives Synthesis, and their Biological Activities: A Review |
| title_full | Bis-Schiff Bases of Isatin Derivatives Synthesis, and their Biological Activities: A Review |
| title_fullStr | Bis-Schiff Bases of Isatin Derivatives Synthesis, and their Biological Activities: A Review |
| title_full_unstemmed | Bis-Schiff Bases of Isatin Derivatives Synthesis, and their Biological Activities: A Review |
| title_short | Bis-Schiff Bases of Isatin Derivatives Synthesis, and their Biological Activities: A Review |
| title_sort | bis schiff bases of isatin derivatives synthesis and their biological activities a review |
| topic | : Isatin, Isatin Bis-Schiff bases, biological activities. |
| url | https://ajps.uomustansiriyah.edu.iq/index.php/AJPS/article/view/827 |
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