METTL3 Is Associated With the Malignancy of Esophageal Squamous Cell Carcinoma and Serves as a Potential Immunotherapy Biomarker

METTL3 Is Associated With the Malignancy of Esophageal Squamous Cell Carcinoma and Serves as a Potential Immunotherapy Biomarker

Methyltransferase-like 3 (METTL3) is an RNA methyltransferase mediating N6 methyladenosine (m6A) modification. Its role in cancer pathogenesis and progression has attracted increasing attention. However, the immunological role, possible immune mechanism, and clinical significance of METTL3 in esopha...

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Bibliographic Details
Main Authors: Yubin Zhou, Songhe Guo, Yiqiu Li, Fangfang Chen, Yaxian Wu, Yi Xiao, Jun An
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Oncology
Subjects:
esophageal squamous cell carcinoma
METTL3
m6A modification
immune infiltration
immunotyping
prognostic model
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.824190/full

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