Fitmix: An R Package for Mixture Modeling of the Budding Yeast <i>S. cerevisiae</i> Replicative Lifespan (RLS) Distributions

Fitmix: An R Package for Mixture Modeling of the Budding Yeast <i>S. cerevisiae</i> Replicative Lifespan (RLS) Distributions

Replicative lifespan (RLS) of the budding yeast is the number of mother cell divisions until senescence and is instrumental to understanding mechanisms of cellular aging. Recent research has shown that replicative aging is heterogeneous, which argues for mixture modeling. The mixture model is a stat...

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Bibliographic Details
Main Authors:	Emine Güven, Hong Qin
Format:	Article
Language:	English
Published:	MDPI AG 2021-06-01
Series:	Applied Sciences
Subjects:	yeast aging mixture modeling Gompertz mixture model Weibull mixture model maximum likelihood estimation Expectation–Maximization (EM)
Online Access:	https://www.mdpi.com/2076-3417/11/13/6114

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