Establishment of an Antiplasmodial Vaccine Based on PfRH5-Encoding RNA Replicons Stabilized by Cationic Liposomes

Establishment of an Antiplasmodial Vaccine Based on PfRH5-Encoding RNA Replicons Stabilized by Cationic Liposomes

Background: Nucleic acid-based vaccines have been studied for the past four decades, but the approval of the first messenger RNA (mRNA) vaccines during the COVID-19 pandemic opened renewed perspectives for the development of similar vaccines against different infectious diseases. Presently available...

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Bibliographic Details
Main Authors: Wesley L. Fotoran, Jamile Ramos da Silva, Christiane Glitz, Luís Carlos de Souza Ferreira, Gerhard Wunderlich
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Pharmaceutics
Subjects:
nucleic acid vaccines
RNA replicons
cationic liposomes
malaria
PfRH5
intradermal immunization
Online Access:https://www.mdpi.com/1999-4923/15/4/1223

Internet

https://www.mdpi.com/1999-4923/15/4/1223

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