Butyrate limits the replication of porcine epidemic diarrhea virus in intestine epithelial cells by enhancing GPR43-mediated IFN-III production

Butyrate limits the replication of porcine epidemic diarrhea virus in intestine epithelial cells by enhancing GPR43-mediated IFN-III production

Porcine epidemic diarrhea virus (PEDV) is a threat to the health of newborn piglets and has a significant impact on the swine industry. Short-chain fatty acids (SCFAs) are gut microbial metabolites that regulate intestinal function through different mechanisms to enhance the intestinal barrier and i...

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Bibliographic Details
Main Authors: Haiyan He, Xuelei Fan, Haiyan Shen, Hongchao Gou, Chunhong Zhang, Zhicheng Liu, Bin Zhang, Nile Wuri, Jianfeng Zhang, Ming Liao, Letu Geri
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Microbiology
Subjects:
porcine epidemic diarrhea virus
butyrate
GPR43
intestinal epithelial cells
IFN-III
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1091807/full

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