Acute Stress Facilitates LTD Induction at Glutamatergic Synapses in the Hippocampal CA1 Region by Activating μ-Opioid Receptors on GABAergic Neurons

Acute Stress Facilitates LTD Induction at Glutamatergic Synapses in the Hippocampal CA1 Region by Activating μ-Opioid Receptors on GABAergic Neurons

Acute stress impairs recall memory through the facilitation of long-term depression (LTD) of hippocampal synaptic transmission. The endogenous opioid system (EOS) plays essential roles in stress-related emotional and physiological responses. Specifically, behavioral studies have shown that the impai...

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Bibliographic Details
Main Authors: Ka-Min Fan, Li-Juan Qiu, Ning Ma, Yi-Nan Du, Zhao-Qiang Qian, Chun-Ling Wei, Jing Han, Wei Ren, Mei-Mei Shi, Zhi-Qiang Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Neuroscience
Subjects:
synaptic plasticity
hippocampus
endogenous opioid system
acute stress
inhibitory transmission
μ-opioid receptors
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.00071/full

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