Seroreactivity to <i>Coxiella burnetii</i> in an Agricultural Population and Prevalence of <i>Coxiella burnetii</i> Infection in Ticks of a Non-Endemic Region for Q Fever in South Korea
<i>Coxiella burnetii</i> infects humans and wild and domesticated animals. Although reported cases on Jeju Island, off the coast of South Korea, are rare, the region is considered to have a high potential for Q fever. We investigated the seroprevalence of antibodies to <i>C. burnet...
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MDPI AG
2021-10-01
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| Series: | Pathogens |
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| Online Access: | https://www.mdpi.com/2076-0817/10/10/1337 |
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| author | Jeong-Rae Yoo Mi-Sun Kim Sang-Taek Heo Hyun-Joo Oh Jung-Hwan Oh Seo-Young Ko Jeong-Ho Kang Sung-Kgun Lee Woo-Seong Jeong Gil-Myeong Seong Hyun-Jung Lee Chul-Hoo Kang Ji-Hyun Moon Keun-Hwa Lee Sung-Wook Song |
| author_facet | Jeong-Rae Yoo Mi-Sun Kim Sang-Taek Heo Hyun-Joo Oh Jung-Hwan Oh Seo-Young Ko Jeong-Ho Kang Sung-Kgun Lee Woo-Seong Jeong Gil-Myeong Seong Hyun-Jung Lee Chul-Hoo Kang Ji-Hyun Moon Keun-Hwa Lee Sung-Wook Song |
| author_sort | Jeong-Rae Yoo |
| collection | DOAJ |
| description | <i>Coxiella burnetii</i> infects humans and wild and domesticated animals. Although reported cases on Jeju Island, off the coast of South Korea, are rare, the region is considered to have a high potential for Q fever. We investigated the seroprevalence of antibodies to <i>C. burnetii</i> in 230 farmers living in ten rural areas on Jeju Island between January 2015 and December 2019. Blood samples were collected and examined for <i>C. burnetii</i> Phase I/II IgM and IgG antibodies. Trained researchers collected ticks from rural areas. Clone XCP-1 16S ribosomal RNA gene sequencing was performed to identify <i>Coxiella</i> species from the collected ticks. The overall seroprevalence of antibodies to <i>C. burnetii</i> in farmers was 35.7%. The seroprevalence was significantly higher in fruit farmers. Of the collected ticks, 5.4% (19/351) of the <i>Haemaphysalis longicornis</i> ticks harbored <i>C. burnetti.</i> A high seroprevalence of antibodies to <i>C. burnetii</i> was observed in this region of Jeju Island, confirming that <i>C. burnetti</i> is endemic. Physicians should thus consider Q fever in the differential diagnosis of patients that present with acute fever after participating in outdoor activities. |
| first_indexed | 2024-03-10T06:17:44Z |
| format | Article |
| id | doaj.art-ee72a6a043f2426cb1a8fc88415acfc6 |
| institution | Directory Open Access Journal |
| issn | 2076-0817 |
| language | English |
| last_indexed | 2024-03-10T06:17:44Z |
| publishDate | 2021-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pathogens |
| spelling | doaj.art-ee72a6a043f2426cb1a8fc88415acfc62023-11-22T19:34:36ZengMDPI AGPathogens2076-08172021-10-011010133710.3390/pathogens10101337Seroreactivity to <i>Coxiella burnetii</i> in an Agricultural Population and Prevalence of <i>Coxiella burnetii</i> Infection in Ticks of a Non-Endemic Region for Q Fever in South KoreaJeong-Rae Yoo0Mi-Sun Kim1Sang-Taek Heo2Hyun-Joo Oh3Jung-Hwan Oh4Seo-Young Ko5Jeong-Ho Kang6Sung-Kgun Lee7Woo-Seong Jeong8Gil-Myeong Seong9Hyun-Jung Lee10Chul-Hoo Kang11Ji-Hyun Moon12Keun-Hwa Lee13Sung-Wook Song14Department of Internal Medicine, College of Medicine, Jeju National University, Jeju 63241, KoreaDepartment of Internal Medicine, Jeju National University Hospital, Jeju 63241, KoreaDepartment of Internal Medicine, College of Medicine, Jeju National University, Jeju 63241, KoreaDepartment of Internal Medicine, Jeju National University Hospital, Jeju 63241, KoreaCenter for Farmers’ Safety and Health, Jeju National University Hospital, Jeju 63241, KoreaCenter for Farmers’ Safety and Health, Jeju National University Hospital, Jeju 63241, KoreaCenter for Farmers’ Safety and Health, Jeju National University Hospital, Jeju 63241, KoreaCenter for Farmers’ Safety and Health, Jeju National University Hospital, Jeju 63241, KoreaDepartment of Internal Medicine, College of Medicine, Jeju National University, Jeju 63241, KoreaDepartment of Internal Medicine, College of Medicine, Jeju National University, Jeju 63241, KoreaCenter for Farmers’ Safety and Health, Jeju National University Hospital, Jeju 63241, KoreaCenter for Farmers’ Safety and Health, Jeju National University Hospital, Jeju 63241, KoreaCenter for Farmers’ Safety and Health, Jeju National University Hospital, Jeju 63241, KoreaDepartment of Microbiology, College of Medicine, Hanyang University, Seoul 04763, KoreaCenter for Farmers’ Safety and Health, Jeju National University Hospital, Jeju 63241, Korea<i>Coxiella burnetii</i> infects humans and wild and domesticated animals. Although reported cases on Jeju Island, off the coast of South Korea, are rare, the region is considered to have a high potential for Q fever. We investigated the seroprevalence of antibodies to <i>C. burnetii</i> in 230 farmers living in ten rural areas on Jeju Island between January 2015 and December 2019. Blood samples were collected and examined for <i>C. burnetii</i> Phase I/II IgM and IgG antibodies. Trained researchers collected ticks from rural areas. Clone XCP-1 16S ribosomal RNA gene sequencing was performed to identify <i>Coxiella</i> species from the collected ticks. The overall seroprevalence of antibodies to <i>C. burnetii</i> in farmers was 35.7%. The seroprevalence was significantly higher in fruit farmers. Of the collected ticks, 5.4% (19/351) of the <i>Haemaphysalis longicornis</i> ticks harbored <i>C. burnetti.</i> A high seroprevalence of antibodies to <i>C. burnetii</i> was observed in this region of Jeju Island, confirming that <i>C. burnetti</i> is endemic. Physicians should thus consider Q fever in the differential diagnosis of patients that present with acute fever after participating in outdoor activities.https://www.mdpi.com/2076-0817/10/10/1337<i>Coxiella burnetii</i>Q fevertick-borne diseaseseroprevalenceSouth Korea |
| spellingShingle | Jeong-Rae Yoo Mi-Sun Kim Sang-Taek Heo Hyun-Joo Oh Jung-Hwan Oh Seo-Young Ko Jeong-Ho Kang Sung-Kgun Lee Woo-Seong Jeong Gil-Myeong Seong Hyun-Jung Lee Chul-Hoo Kang Ji-Hyun Moon Keun-Hwa Lee Sung-Wook Song Seroreactivity to <i>Coxiella burnetii</i> in an Agricultural Population and Prevalence of <i>Coxiella burnetii</i> Infection in Ticks of a Non-Endemic Region for Q Fever in South Korea Pathogens <i>Coxiella burnetii</i> Q fever tick-borne disease seroprevalence South Korea |
| title | Seroreactivity to <i>Coxiella burnetii</i> in an Agricultural Population and Prevalence of <i>Coxiella burnetii</i> Infection in Ticks of a Non-Endemic Region for Q Fever in South Korea |
| title_full | Seroreactivity to <i>Coxiella burnetii</i> in an Agricultural Population and Prevalence of <i>Coxiella burnetii</i> Infection in Ticks of a Non-Endemic Region for Q Fever in South Korea |
| title_fullStr | Seroreactivity to <i>Coxiella burnetii</i> in an Agricultural Population and Prevalence of <i>Coxiella burnetii</i> Infection in Ticks of a Non-Endemic Region for Q Fever in South Korea |
| title_full_unstemmed | Seroreactivity to <i>Coxiella burnetii</i> in an Agricultural Population and Prevalence of <i>Coxiella burnetii</i> Infection in Ticks of a Non-Endemic Region for Q Fever in South Korea |
| title_short | Seroreactivity to <i>Coxiella burnetii</i> in an Agricultural Population and Prevalence of <i>Coxiella burnetii</i> Infection in Ticks of a Non-Endemic Region for Q Fever in South Korea |
| title_sort | seroreactivity to i coxiella burnetii i in an agricultural population and prevalence of i coxiella burnetii i infection in ticks of a non endemic region for q fever in south korea |
| topic | <i>Coxiella burnetii</i> Q fever tick-borne disease seroprevalence South Korea |
| url | https://www.mdpi.com/2076-0817/10/10/1337 |
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