Blood oxygen regulation via P2Y12R expressed in the carotid body

Blood oxygen regulation via P2Y12R expressed in the carotid body

Abstract Background Peripheral blood oxygen monitoring via chemoreceptors in the carotid body (CB) is an integral function of the autonomic cardiorespiratory regulation. The presence of the purinergic P2Y12 receptor (P2Y12R) has been implicated in CB; however, the exact role of the receptor in O2 se...

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Main Authors: András Iring, Mária Baranyi, Bernadett Iring-Varga, Paula Mut-Arbona, Zsuzsanna T. Gál, Dorina Nagy, László Hricisák, János Varga, Zoltán Benyó, Beáta Sperlágh
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Respiratory Research
Subjects:
Chemoreceptor
Hypoxia
O2 sensing
Purinergic signalling
Signal transduction
Cardiorespiratory regulation
Online Access:https://doi.org/10.1186/s12931-024-02680-x

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