Chronic Rhinosinusitis with Nasal Polyps: A Survey on Routine Management and Evaluation of Disease Control in Practice
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a disease with a significant impact on quality of life. The overall goal of CRSwNP management, as with other chronic conditions, is to achieve “disease control”, and for that reason, a definition of control of disease is pivotal in deciding the be...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-10-01
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| Series: | Journal of Personalized Medicine |
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| Online Access: | https://www.mdpi.com/2075-4426/13/11/1531 |
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| author | Eugenio De Corso Giancarlo Ottaviano Carlotta Pipolo Elena Cantone Davide Mattavelli Matteo Alicandri-Ciufelli Daniela Lucidi Marco Caminati Gianenrico Senna Carlo Cavaliere Angelo Ghidini Stefania Gallo Alberto Macchi Sara Torretta Veronica Seccia Massimiliano Garzaro Gian Luca Fadda Matteo Trimarchi Ernesto Pasquini Fabio Pagella Frank Rikki Canevari Andrea Preti Ignazio La Mantia Jacopo Galli |
| author_facet | Eugenio De Corso Giancarlo Ottaviano Carlotta Pipolo Elena Cantone Davide Mattavelli Matteo Alicandri-Ciufelli Daniela Lucidi Marco Caminati Gianenrico Senna Carlo Cavaliere Angelo Ghidini Stefania Gallo Alberto Macchi Sara Torretta Veronica Seccia Massimiliano Garzaro Gian Luca Fadda Matteo Trimarchi Ernesto Pasquini Fabio Pagella Frank Rikki Canevari Andrea Preti Ignazio La Mantia Jacopo Galli |
| author_sort | Eugenio De Corso |
| collection | DOAJ |
| description | Chronic rhinosinusitis with nasal polyps (CRSwNP) is a disease with a significant impact on quality of life. The overall goal of CRSwNP management, as with other chronic conditions, is to achieve “disease control”, and for that reason, a definition of control of disease is pivotal in deciding the best treatment strategy. Although many staging systems have already been developed to evaluate the disease, disease control is not yet to be standardized, and a specific tool that is consistently applied and accepted by all practitioners is still missing in daily clinical practice. To gain an overview of the implementation and limitations of existing guidelines and to shed light on real-life definitions of control and disease severity, we conducted a nationwide survey of otorhinolaryngologists routinely treating CRSwNP to identify unmet clinical needs in Italy. The results showed homogeneous responses regarding the knowledge contained in international guidelines while highlighting the difficulty of their implementation in day-to-day practice. Respondents called attention to the importance of clinical symptoms, giving more weight to the patient’s perspective. Among the symptoms to be considered, respondents emphasized nasal obstruction, followed by loss of sense of smell and rhinorrhea. Others also believe that the physician’s perspective should be considered, and the inclusion of endoscopy as a measure of control was warranted by many. The need for a specific tool that is able to unequivocally ascertain disease control is increasingly pivotal in this new era of biologics for treating CRSwNP. |
| first_indexed | 2024-03-09T16:41:37Z |
| format | Article |
| id | doaj.art-ee7f00fd3e434caea2b9ff29c92a2ede |
| institution | Directory Open Access Journal |
| issn | 2075-4426 |
| language | English |
| last_indexed | 2024-03-09T16:41:37Z |
| publishDate | 2023-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Personalized Medicine |
| spelling | doaj.art-ee7f00fd3e434caea2b9ff29c92a2ede2023-11-24T14:51:17ZengMDPI AGJournal of Personalized Medicine2075-44262023-10-011311153110.3390/jpm13111531Chronic Rhinosinusitis with Nasal Polyps: A Survey on Routine Management and Evaluation of Disease Control in PracticeEugenio De Corso0Giancarlo Ottaviano1Carlotta Pipolo2Elena Cantone3Davide Mattavelli4Matteo Alicandri-Ciufelli5Daniela Lucidi6Marco Caminati7Gianenrico Senna8Carlo Cavaliere9Angelo Ghidini10Stefania Gallo11Alberto Macchi12Sara Torretta13Veronica Seccia14Massimiliano Garzaro15Gian Luca Fadda16Matteo Trimarchi17Ernesto Pasquini18Fabio Pagella19Frank Rikki Canevari20Andrea Preti21Ignazio La Mantia22Jacopo Galli23Otolaryngology, Head and Neck Surgery, Rhinology, A. Gemelli University Hospital Foundation, IRCSS, 00168 Rome, ItalyDepartment of Neurosciences, Otolaryngology Section, University of Padova, 35122 Padova, ItalyOtolaryngology Unit, ASST Santi Paolo e Carlo, Department of Health Sciences, University of Milan, 20142 Milan, ItalyDepartment of Neuroscience, Reproductive and Odontostomatological Sciences-ENT Section, University of Naples 29 Federico II, 80131 Naples, ItalyUnit of Otorhinolaryngology-Head and Neck Surgery, ASST Spedali Civili Brescia, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, 25123 Brescia, ItalyDepartment of Otorhinolaryngology Head and Neck Surgery, Azienda Ospedaliero-Universitaria Policlinico di Modena, 41124 Modena, ItalyDepartment of Otorhinolaryngology Head and Neck Surgery, Azienda Ospedaliero-Universitaria Policlinico di Modena, 41124 Modena, ItalyDepartment of Medicine, University of Verona and Verona University Hospital, 37134 Verona, ItalyDepartment of Medicine, University of Verona and Verona University Hospital, 37134 Verona, ItalyDepartment of Sense Organs, Sapienza University of Rome, 00185 Rome, ItalyENT Department, Azienda USL Reggio Emilia-IRCCS, 42123 Reggio Emilia, ItalyOtorinolaryngology Unit, Head and Neck Department, ASST Sette Laghi and UPLOAD Research Center, University of Insubria, 21100 Varese, ItalyOtorinolaryngology Unit, Head and Neck Department, ASST Sette Laghi and UPLOAD Research Center, University of Insubria, 21100 Varese, ItalyFondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Department of Clinical Sciences and Community Health, University of Milan, 20122 Milan, ItalyOtolaryngology, Audiology and Phoniatric Operative Unit, Department of Surgical, Medical, Molecular Pathology and Critical Care Medicine, Azienda Ospedaliera Universitaria Pisana, University of Pisa, 56124 Pisa, ItalyDepartment of Otorhinolaryngology, Rhinology Unit, Eastern Piedmont University-Maggiore Hospital, 28100 Novara, ItalyDepartment of Otorhinolaryngology, San Luigi Gonzaga Hospital, University of Turin, 10043 Orbassano, ItalyOtorhinolaryngology Unit, Head and Neck Department, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, 20132 Milan, ItalyOtorhinolaryngology Unit, Dip Chirurgie Specialistiche, Ospedale Bellaria AUSL BO, 47814 Bologna, ItalyDepartment of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, ItalyOtorhinolaryngology Unit, IRCCS Policlinico San Martino Genova, Dipartimento 1 DISC Università di Genova, 16124 Gernova, ItalyDepartment of Otorhinolaryngology, Ospedale San Giuseppe IRCCS Multimedica Milan, 20099 Milan, ItalyDepartment of Medical-Surgical Sciences and Advanced Technologies-“G.F. Ingrassia” Director of E.N.T. Unit P.O. “G. Rodolico” University of Catania, 95123 Catania, ItalyDepartment of Head, Neck and Sensory Organs, Catholic University of The Sacred Heart, 00168 Rome, ItalyChronic rhinosinusitis with nasal polyps (CRSwNP) is a disease with a significant impact on quality of life. The overall goal of CRSwNP management, as with other chronic conditions, is to achieve “disease control”, and for that reason, a definition of control of disease is pivotal in deciding the best treatment strategy. Although many staging systems have already been developed to evaluate the disease, disease control is not yet to be standardized, and a specific tool that is consistently applied and accepted by all practitioners is still missing in daily clinical practice. To gain an overview of the implementation and limitations of existing guidelines and to shed light on real-life definitions of control and disease severity, we conducted a nationwide survey of otorhinolaryngologists routinely treating CRSwNP to identify unmet clinical needs in Italy. The results showed homogeneous responses regarding the knowledge contained in international guidelines while highlighting the difficulty of their implementation in day-to-day practice. Respondents called attention to the importance of clinical symptoms, giving more weight to the patient’s perspective. Among the symptoms to be considered, respondents emphasized nasal obstruction, followed by loss of sense of smell and rhinorrhea. Others also believe that the physician’s perspective should be considered, and the inclusion of endoscopy as a measure of control was warranted by many. The need for a specific tool that is able to unequivocally ascertain disease control is increasingly pivotal in this new era of biologics for treating CRSwNP.https://www.mdpi.com/2075-4426/13/11/1531CRSwNPdisease controldisease severitybiologicsendoscopic sinus surgery |
| spellingShingle | Eugenio De Corso Giancarlo Ottaviano Carlotta Pipolo Elena Cantone Davide Mattavelli Matteo Alicandri-Ciufelli Daniela Lucidi Marco Caminati Gianenrico Senna Carlo Cavaliere Angelo Ghidini Stefania Gallo Alberto Macchi Sara Torretta Veronica Seccia Massimiliano Garzaro Gian Luca Fadda Matteo Trimarchi Ernesto Pasquini Fabio Pagella Frank Rikki Canevari Andrea Preti Ignazio La Mantia Jacopo Galli Chronic Rhinosinusitis with Nasal Polyps: A Survey on Routine Management and Evaluation of Disease Control in Practice Journal of Personalized Medicine CRSwNP disease control disease severity biologics endoscopic sinus surgery |
| title | Chronic Rhinosinusitis with Nasal Polyps: A Survey on Routine Management and Evaluation of Disease Control in Practice |
| title_full | Chronic Rhinosinusitis with Nasal Polyps: A Survey on Routine Management and Evaluation of Disease Control in Practice |
| title_fullStr | Chronic Rhinosinusitis with Nasal Polyps: A Survey on Routine Management and Evaluation of Disease Control in Practice |
| title_full_unstemmed | Chronic Rhinosinusitis with Nasal Polyps: A Survey on Routine Management and Evaluation of Disease Control in Practice |
| title_short | Chronic Rhinosinusitis with Nasal Polyps: A Survey on Routine Management and Evaluation of Disease Control in Practice |
| title_sort | chronic rhinosinusitis with nasal polyps a survey on routine management and evaluation of disease control in practice |
| topic | CRSwNP disease control disease severity biologics endoscopic sinus surgery |
| url | https://www.mdpi.com/2075-4426/13/11/1531 |
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