Catalytic System for Cross-Coupling of Heteroaryl Iodides with a Nitronyl Nitroxide Gold Derivative at Room Temperature
A simple and highly effective methodology for the cross-coupling of heteroaryl iodides with NN–AuPPh<sub>3</sub> at room temperature is reported. The protocol is based on a novel catalytic system consisting of Pd<sub>2</sub>(dba)<sub>3</sub>·CHCl<sub>3</s...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-11-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/28/22/7661 |
| Summary: | A simple and highly effective methodology for the cross-coupling of heteroaryl iodides with NN–AuPPh<sub>3</sub> at room temperature is reported. The protocol is based on a novel catalytic system consisting of Pd<sub>2</sub>(dba)<sub>3</sub>·CHCl<sub>3</sub> and the phosphine ligand <sup>Me</sup>CgPPh having an adamantane-like framework. The present protocol was found to be well compatible with various heteroaryl iodides, thus opening new horizons in directed synthesis of functionalized nitronyl nitroxides and high-spin molecules. |
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| ISSN: | 1420-3049 |