Advances in Integrating Genomics and Bioinformatics in the Plant Breeding Pipeline

With the global human population growing rapidly, agricultural production must increase to meet crop demand. Improving crops through breeding is a sustainable approach to increase yield and yield stability without intensifying the use of fertilisers and pesticides. Current advances in genomics and b...

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Main Authors: Haifei Hu, Armin Scheben, David Edwards
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:Agriculture
Subjects:
Online Access:http://www.mdpi.com/2077-0472/8/6/75
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author Haifei Hu
Armin Scheben
David Edwards
author_facet Haifei Hu
Armin Scheben
David Edwards
author_sort Haifei Hu
collection DOAJ
description With the global human population growing rapidly, agricultural production must increase to meet crop demand. Improving crops through breeding is a sustainable approach to increase yield and yield stability without intensifying the use of fertilisers and pesticides. Current advances in genomics and bioinformatics provide opportunities for accelerating crop improvement. The rise of third generation sequencing technologies is helping overcome challenges in plant genome assembly caused by polyploidy and frequent repetitive elements. As a result, high-quality crop reference genomes are increasingly available, benefitting downstream analyses such as variant calling and association mapping that identify breeding targets in the genome. Machine learning also helps identify genomic regions of agronomic value by facilitating functional annotation of genomes and enabling real-time high-throughput phenotyping of agronomic traits in the glasshouse and in the field. Furthermore, crop databases that integrate the growing volume of genotype and phenotype data provide a valuable resource for breeders and an opportunity for data mining approaches to uncover novel trait-associated candidate genes. As knowledge of crop genetics expands, genomic selection and genome editing hold promise for breeding diseases-resistant and stress-tolerant crops with high yields.
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spelling doaj.art-ee892cc3971d483d83d194ee6155d71e2022-12-21T18:57:39ZengMDPI AGAgriculture2077-04722018-05-01867510.3390/agriculture8060075agriculture8060075Advances in Integrating Genomics and Bioinformatics in the Plant Breeding PipelineHaifei Hu0Armin Scheben1David Edwards2School of Biological Sciences and Institute of Agriculture, The University of Western Australia, Perth 6009, AustraliaSchool of Biological Sciences and Institute of Agriculture, The University of Western Australia, Perth 6009, AustraliaSchool of Biological Sciences and Institute of Agriculture, The University of Western Australia, Perth 6009, AustraliaWith the global human population growing rapidly, agricultural production must increase to meet crop demand. Improving crops through breeding is a sustainable approach to increase yield and yield stability without intensifying the use of fertilisers and pesticides. Current advances in genomics and bioinformatics provide opportunities for accelerating crop improvement. The rise of third generation sequencing technologies is helping overcome challenges in plant genome assembly caused by polyploidy and frequent repetitive elements. As a result, high-quality crop reference genomes are increasingly available, benefitting downstream analyses such as variant calling and association mapping that identify breeding targets in the genome. Machine learning also helps identify genomic regions of agronomic value by facilitating functional annotation of genomes and enabling real-time high-throughput phenotyping of agronomic traits in the glasshouse and in the field. Furthermore, crop databases that integrate the growing volume of genotype and phenotype data provide a valuable resource for breeders and an opportunity for data mining approaches to uncover novel trait-associated candidate genes. As knowledge of crop genetics expands, genomic selection and genome editing hold promise for breeding diseases-resistant and stress-tolerant crops with high yields.http://www.mdpi.com/2077-0472/8/6/75breedingcropsgenomicsthird generation sequencing
spellingShingle Haifei Hu
Armin Scheben
David Edwards
Advances in Integrating Genomics and Bioinformatics in the Plant Breeding Pipeline
Agriculture
breeding
crops
genomics
third generation sequencing
title Advances in Integrating Genomics and Bioinformatics in the Plant Breeding Pipeline
title_full Advances in Integrating Genomics and Bioinformatics in the Plant Breeding Pipeline
title_fullStr Advances in Integrating Genomics and Bioinformatics in the Plant Breeding Pipeline
title_full_unstemmed Advances in Integrating Genomics and Bioinformatics in the Plant Breeding Pipeline
title_short Advances in Integrating Genomics and Bioinformatics in the Plant Breeding Pipeline
title_sort advances in integrating genomics and bioinformatics in the plant breeding pipeline
topic breeding
crops
genomics
third generation sequencing
url http://www.mdpi.com/2077-0472/8/6/75
work_keys_str_mv AT haifeihu advancesinintegratinggenomicsandbioinformaticsintheplantbreedingpipeline
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