Comparison of urinary adiponectin in the presence of metabolic syndrome in peri- and postmenopausal women
Abstract Objectives To find the association between urinary adiponectin and metabolic syndrome (MetS) in peri- and postmenopausal women and its potential application as a noninvasive screening for MetS. Methods A cross-sectional study was conducted in healthy peri- and postmenopausal women (defined...
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| Format: | Article |
| Language: | English |
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BMC
2022-03-01
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| Series: | BMC Women's Health |
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| Online Access: | https://doi.org/10.1186/s12905-022-01655-8 |
| _version_ | 1818315634892603392 |
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| author | Patsama Vichinsartvichai Rattana Teeramara Titima Jirasawas Prirayapak Sakoonwatanyoo |
| author_facet | Patsama Vichinsartvichai Rattana Teeramara Titima Jirasawas Prirayapak Sakoonwatanyoo |
| author_sort | Patsama Vichinsartvichai |
| collection | DOAJ |
| description | Abstract Objectives To find the association between urinary adiponectin and metabolic syndrome (MetS) in peri- and postmenopausal women and its potential application as a noninvasive screening for MetS. Methods A cross-sectional study was conducted in healthy peri- and postmenopausal women (defined by STRAW + 10 staging) aged at least 40 years who attended annual check-ups or menopause clinics were recruited. Baseline demographic data, MENQOL, anthropometric measurements, blood pressure, laboratory (FBS, total cholesterol, HDL-C, LDL-C, TG), and urinary adiponectin were collected. The MetS was diagnosed according to JIS 2009. Results 290 peri- and postmenopausal women had participated. The prevalence of Mets among our participants was 18%. Urinary adiponectin levels were similar in peri- and postmenopausal women with and without MetS (2.6 ± 2.2 vs. 2.3 ± 1.9 ng/mL, respectively, P = 0.55). Urinary adiponectin provides no diagnostic value for MetS (AUC = 0.516). Conclusions Urinary adiponectin has no role in screening and diagnosing MetS in peri- and postmenopausal women. The quest toward noninvasive screening for MetS is still going on. |
| first_indexed | 2024-12-13T09:08:40Z |
| format | Article |
| id | doaj.art-ee8a8ebe5bf844468180ce53bde4f0ae |
| institution | Directory Open Access Journal |
| issn | 1472-6874 |
| language | English |
| last_indexed | 2024-12-13T09:08:40Z |
| publishDate | 2022-03-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Women's Health |
| spelling | doaj.art-ee8a8ebe5bf844468180ce53bde4f0ae2022-12-21T23:53:01ZengBMCBMC Women's Health1472-68742022-03-012211710.1186/s12905-022-01655-8Comparison of urinary adiponectin in the presence of metabolic syndrome in peri- and postmenopausal womenPatsama Vichinsartvichai0Rattana Teeramara1Titima Jirasawas2Prirayapak Sakoonwatanyoo3Department of Obstetrics and Gynecology, Faculty of Medicine Vajira Hospital, Navamindradhiraj UniversityDepartment of Obstetrics and Gynecology, Faculty of Medicine Vajira Hospital, Navamindradhiraj UniversityDepartment of Obstetrics and Gynecology, Faculty of Medicine Vajira Hospital, Navamindradhiraj UniversityDepartment of Clinical Pathology, Faculty of Medicine Vajira Hospital, Navamindradhiraj UniversityAbstract Objectives To find the association between urinary adiponectin and metabolic syndrome (MetS) in peri- and postmenopausal women and its potential application as a noninvasive screening for MetS. Methods A cross-sectional study was conducted in healthy peri- and postmenopausal women (defined by STRAW + 10 staging) aged at least 40 years who attended annual check-ups or menopause clinics were recruited. Baseline demographic data, MENQOL, anthropometric measurements, blood pressure, laboratory (FBS, total cholesterol, HDL-C, LDL-C, TG), and urinary adiponectin were collected. The MetS was diagnosed according to JIS 2009. Results 290 peri- and postmenopausal women had participated. The prevalence of Mets among our participants was 18%. Urinary adiponectin levels were similar in peri- and postmenopausal women with and without MetS (2.6 ± 2.2 vs. 2.3 ± 1.9 ng/mL, respectively, P = 0.55). Urinary adiponectin provides no diagnostic value for MetS (AUC = 0.516). Conclusions Urinary adiponectin has no role in screening and diagnosing MetS in peri- and postmenopausal women. The quest toward noninvasive screening for MetS is still going on.https://doi.org/10.1186/s12905-022-01655-8Urinary adiponectinMetabolic syndromeMenopauseMenopausal transition |
| spellingShingle | Patsama Vichinsartvichai Rattana Teeramara Titima Jirasawas Prirayapak Sakoonwatanyoo Comparison of urinary adiponectin in the presence of metabolic syndrome in peri- and postmenopausal women BMC Women's Health Urinary adiponectin Metabolic syndrome Menopause Menopausal transition |
| title | Comparison of urinary adiponectin in the presence of metabolic syndrome in peri- and postmenopausal women |
| title_full | Comparison of urinary adiponectin in the presence of metabolic syndrome in peri- and postmenopausal women |
| title_fullStr | Comparison of urinary adiponectin in the presence of metabolic syndrome in peri- and postmenopausal women |
| title_full_unstemmed | Comparison of urinary adiponectin in the presence of metabolic syndrome in peri- and postmenopausal women |
| title_short | Comparison of urinary adiponectin in the presence of metabolic syndrome in peri- and postmenopausal women |
| title_sort | comparison of urinary adiponectin in the presence of metabolic syndrome in peri and postmenopausal women |
| topic | Urinary adiponectin Metabolic syndrome Menopause Menopausal transition |
| url | https://doi.org/10.1186/s12905-022-01655-8 |
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