The Regulation of Collagen Processing by miRNAs in Disease and Possible Implications for Bone Turnover

The Regulation of Collagen Processing by miRNAs in Disease and Possible Implications for Bone Turnover

This article describes several recent examples of miRNA governing the regulation of the gene expression involved in bone matrix construction. We present the impact of miRNA on the subsequent steps in the formation of collagen type I. Collagen type I is a main factor of mechanical bone stiffness beca...

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Bibliographic Details
Main Authors: Tomasz P. Lehmann, Urszula Guderska, Klaudia Kałek, Maria Marzec, Agnieszka Urbanek, Alicja Czernikiewicz, Maria Sąsiadek, Paweł Karpiński, Andrzej Pławski, Maciej Głowacki, Paweł P. Jagodziński
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
miRNA
extracellular matrix
collagen type I
bone turnover
non-collagenous proteins
Online Access:https://www.mdpi.com/1422-0067/23/1/91

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