Acute gastroenteritis—changes to the recommended original oral rehydrating salts: a review

The World Health Organization recommended a formulation of oral rehydration salts as the intervention of choice for the treatment of acute gastroenteritis. While of value for the replacement of fluids and electrolytes, the formulation does not reduce stool volume, frequency, or symptom duration. Thi...

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Main Authors: Carlos Lifschitz, Oleksii Kozhevnikov, Christine Oesterling, Amira Anbar, Steven Walker
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Pediatrics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2023.1294490/full
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author Carlos Lifschitz
Oleksii Kozhevnikov
Christine Oesterling
Amira Anbar
Steven Walker
author_facet Carlos Lifschitz
Oleksii Kozhevnikov
Christine Oesterling
Amira Anbar
Steven Walker
author_sort Carlos Lifschitz
collection DOAJ
description The World Health Organization recommended a formulation of oral rehydration salts as the intervention of choice for the treatment of acute gastroenteritis. While of value for the replacement of fluids and electrolytes, the formulation does not reduce stool volume, frequency, or symptom duration. This may prevent wide acceptance. To increase tolerability, shorten the duration of diarrhea and improve parental quality of life, several modifications to the original formula have been proposed. These include; low osmolarity, rice-based, glucose polymers as an alternative to glucose, the addition of probiotics, prebiotics and/or zinc, and various other ingredients. Here we summarize evidence regarding such changes and additions.
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spelling doaj.art-ee8c423ddb7849718d77d3a89fc85a952023-12-18T07:07:45ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602023-12-011110.3389/fped.2023.12944901294490Acute gastroenteritis—changes to the recommended original oral rehydrating salts: a reviewCarlos Lifschitz0Oleksii Kozhevnikov1Christine Oesterling2Amira Anbar3Steven Walker4Hospital Italiano de Buenos Aires, Buenos Aires, ArgentinaMedibiotiX GmbH, Baden-Baden, GermanyEastmead Surgery, Greenford, and Imperial College London, London, United KingdomSt. Gilesmedical, London, United KingdomSt. Gilesmedical (London & Berlin) & University of Applied Sciences, Bremen, GermanyThe World Health Organization recommended a formulation of oral rehydration salts as the intervention of choice for the treatment of acute gastroenteritis. While of value for the replacement of fluids and electrolytes, the formulation does not reduce stool volume, frequency, or symptom duration. This may prevent wide acceptance. To increase tolerability, shorten the duration of diarrhea and improve parental quality of life, several modifications to the original formula have been proposed. These include; low osmolarity, rice-based, glucose polymers as an alternative to glucose, the addition of probiotics, prebiotics and/or zinc, and various other ingredients. Here we summarize evidence regarding such changes and additions.https://www.frontiersin.org/articles/10.3389/fped.2023.1294490/fullreviewacute gastroenteritis (AGE)oral rehydrating solutionprobiotics and prebioticszinclow osmolar oral rehydration solution
spellingShingle Carlos Lifschitz
Oleksii Kozhevnikov
Christine Oesterling
Amira Anbar
Steven Walker
Acute gastroenteritis—changes to the recommended original oral rehydrating salts: a review
Frontiers in Pediatrics
review
acute gastroenteritis (AGE)
oral rehydrating solution
probiotics and prebiotics
zinc
low osmolar oral rehydration solution
title Acute gastroenteritis—changes to the recommended original oral rehydrating salts: a review
title_full Acute gastroenteritis—changes to the recommended original oral rehydrating salts: a review
title_fullStr Acute gastroenteritis—changes to the recommended original oral rehydrating salts: a review
title_full_unstemmed Acute gastroenteritis—changes to the recommended original oral rehydrating salts: a review
title_short Acute gastroenteritis—changes to the recommended original oral rehydrating salts: a review
title_sort acute gastroenteritis changes to the recommended original oral rehydrating salts a review
topic review
acute gastroenteritis (AGE)
oral rehydrating solution
probiotics and prebiotics
zinc
low osmolar oral rehydration solution
url https://www.frontiersin.org/articles/10.3389/fped.2023.1294490/full
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