Artralgia inducida por levofloxacina: Reporte de un caso

Woman who initiated second-line rescue therapy for Helicobacter pylori with levofloxacin one gram every 12 hours, amoxicillin 500 mg every 8 hours and lansoprazole 40 mg every 24 hours. On the fifth day of treatment, she manifested generalized myalgia followed by bilateral knee and elbow arthralgia...

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Main Author: María Alejandra Montoya-Giraldo
Format: Article
Language:English
Published: Asociación Colombiana de Infectología 2019-04-01
Series:Infectio
Subjects:
Online Access:https://www.revistainfectio.org/index.php/infectio/article/view/816
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author María Alejandra Montoya-Giraldo
author_facet María Alejandra Montoya-Giraldo
author_sort María Alejandra Montoya-Giraldo
collection DOAJ
description Woman who initiated second-line rescue therapy for Helicobacter pylori with levofloxacin one gram every 12 hours, amoxicillin 500 mg every 8 hours and lansoprazole 40 mg every 24 hours. On the fifth day of treatment, she manifested generalized myalgia followed by bilateral knee and elbow arthralgia with limitation of movements. On the seventh day, without improvement, the patient discontinues the medication and achieve complete resolution of the symptoms one week later. There were no sequelae, no complications, no re-exposure to the drug. The case was classified as probable attaining a score of seven under the Naranjo’s scale. This case reminds us that administration of fluoroquinolones may be associated with arthralgia and acute reversible arthropathy and should be the first diagnostic suspicion in patients without comorbidity.
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spelling doaj.art-ee910318d472439792944228f5e34ba42022-12-22T03:18:15ZengAsociación Colombiana de InfectologíaInfectio0123-93922019-04-0123440540810.22354/in.v23i4.816Artralgia inducida por levofloxacina: Reporte de un casoMaría Alejandra Montoya-Giraldo0CIEMTO: Centro de Información y Estudio de Medicamentos y Tóxicos, Departamento de Farmacología y Toxicología, Facultad de Medicina, Universidad de Antioquia, Medellín, ColombiaWoman who initiated second-line rescue therapy for Helicobacter pylori with levofloxacin one gram every 12 hours, amoxicillin 500 mg every 8 hours and lansoprazole 40 mg every 24 hours. On the fifth day of treatment, she manifested generalized myalgia followed by bilateral knee and elbow arthralgia with limitation of movements. On the seventh day, without improvement, the patient discontinues the medication and achieve complete resolution of the symptoms one week later. There were no sequelae, no complications, no re-exposure to the drug. The case was classified as probable attaining a score of seven under the Naranjo’s scale. This case reminds us that administration of fluoroquinolones may be associated with arthralgia and acute reversible arthropathy and should be the first diagnostic suspicion in patients without comorbidity.https://www.revistainfectio.org/index.php/infectio/article/view/816arthropathylevofloxacindrug-related side effects and adverse reactionsgastritis
spellingShingle María Alejandra Montoya-Giraldo
Artralgia inducida por levofloxacina: Reporte de un caso
Infectio
arthropathy
levofloxacin
drug-related side effects and adverse reactions
gastritis
title Artralgia inducida por levofloxacina: Reporte de un caso
title_full Artralgia inducida por levofloxacina: Reporte de un caso
title_fullStr Artralgia inducida por levofloxacina: Reporte de un caso
title_full_unstemmed Artralgia inducida por levofloxacina: Reporte de un caso
title_short Artralgia inducida por levofloxacina: Reporte de un caso
title_sort artralgia inducida por levofloxacina reporte de un caso
topic arthropathy
levofloxacin
drug-related side effects and adverse reactions
gastritis
url https://www.revistainfectio.org/index.php/infectio/article/view/816
work_keys_str_mv AT mariaalejandramontoyagiraldo artralgiainducidaporlevofloxacinareportedeuncaso