T Cell Repertoire Homogeneity and Blood-Gut Overlap in Patients With Inflammatory Bowel DiseaseSummary

T Cell Repertoire Homogeneity and Blood-Gut Overlap in Patients With Inflammatory Bowel DiseaseSummary

Background & Aims: Inflammatory bowel disease (IBD) causes a marked increase in the number of T cells in the intestinal mucosa. Debate exists about whether these excess cells arise from local clonal proliferation or recruitment from the periphery. Methods: CD8+ T cells were sorted from colon...

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Bibliographic Details
Main Authors: Kyle G. Williams, Ramya Kongala, Donna M. Shows, Andrew J. Konecny, Duncan C. Hindmarch, Astrid S. Clarke, James D. Lord
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
TCR
MAIT
CD8
IBD
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X23001650

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