| Summary: | Summary: Radiation-induced angiosarcoma of the breast (R-AS) is a rare form of malignancy which can develop after breast radiotherapy used in the adjuvant treatment of breast cancer.R-AS poses significant management challenges owing to a high recurrence rate and poor overall survival. Although optimal management of R-AS remains unclear, surgical excision with wide resection margins is typically recommended. The resultant chest wall defects tend to be large and pose a number of reconstructive challenges, especially when selecting the optimal method of soft tissue coverage in patients who are not suitable for microvascular free-flap techniques (either from a medical/anesthetic risk perspective or due to inadequate volume at the donor site).In this case report, we present a case of a 66-year-old female who was treated for high grade R-AS with a mastectomy using a 5cm resection margin with excision of the sternal head of pectoralis major. Subsequent soft tissue coverage of the massive defect was completed using a combination of abdominal advancement and pedicled latissimus dorsi myocutaneous flaps. The patient has now been disease free for 50 months following her surgery.
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