A Human Monoclonal Antibody against Hepatitis B Surface Antigen with Potent Neutralizing Activity.

A Human Monoclonal Antibody against Hepatitis B Surface Antigen with Potent Neutralizing Activity.

We describe the production and characterization of human monoclonal antibodies (mAb) specific for the major hepatitis B virus (HBV) S protein. The mAbs, two IgG1κ and one IgG1λ, were secreted by B-cell clones obtained from peripheral blood mononuclear cells (PBMC) of one person convalescent from acu...

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Bibliographic Details
Main Authors: Antonella Cerino, Corinna M Bremer, Dieter Glebe, Mario U Mondelli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0125704

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