Pairwise sequence similarity mapping with PaSiMap: Reclassification of immunoglobulin domains from titin as case study
Sequence comparison is critical for the functional assignment of newly identified protein genes. As uncharacterized protein sequences accumulate, there is an increasing need for sensitive tools for their classification. Here, we present a novel multidimensional scaling pipeline, PaSiMap, which creat...
Main Authors: | Kathy Su, Olga Mayans, Kay Diederichs, Jennifer R. Fleming |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2022-01-01
|
Series: | Computational and Structural Biotechnology Journal |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2001037022004391 |
Similar Items
-
Immunological and Structural Characterization of Titin Main Immunogenic Region; I110 Domain Is the Target of Titin Antibodies in Myasthenia Gravis
by: Christos Stergiou, et al.
Published: (2023-02-01) -
Interdomain Linker Effect on the Mechanical Stability of Ig Domains in Titin
by: Bei Tong, et al.
Published: (2022-08-01) -
Effect of titin phosphorylation on degradation of titin from skeletal muscles
by: Ying Wang, et al.
Published: (2023-07-01) -
Titin kinase is an inactive pseudokinase scaffold that supports MuRF1 recruitment to the sarcomeric M-line
by: Julijus Bogomolovas, et al.
Published: (2014-01-01) -
Titin N2A Domain and Its Interactions at the Sarcomere
by: Adeleye O. Adewale, et al.
Published: (2021-07-01)