Subcellular Localization of Matrin 3 Containing Mutations Associated with ALS and Distal Myopathy.

Subcellular Localization of Matrin 3 Containing Mutations Associated with ALS and Distal Myopathy.

Mutations in Matrin 3 [MATR3], an RNA- and DNA-binding protein normally localized to the nucleus, have been linked to amyotrophic lateral sclerosis (ALS) and distal myopathies. In the present study, we have used transient transfection of cultured cell lines to examine the impact of different disease...

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Bibliographic Details
Main Authors: M Carolina Gallego-Iradi, Alexis M Clare, Hilda H Brown, Christopher Janus, Jada Lewis, David R Borchelt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4631352?pdf=render

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