Antiphospholipid syndrome and acute myocardial infarction: Treatment with thrombectomy and abciximab
Antiphospholipid syndrome (APS) is an autoimmune coagulation disorder that manifests clinically as venous and arterial thrombosis, and may affect any tissue or organ. Coronary artery involvement, however, is very rare. Case reports in the literature describing patients with coronary acute syndrome a...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2014-07-01
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| Series: | Revista Portuguesa de Cardiologia |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0870255114001528 |
| _version_ | 1818507048722104320 |
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| author | Vicens Martí Filipe Seixo Miguel Santaló Antonio Serra |
| author_facet | Vicens Martí Filipe Seixo Miguel Santaló Antonio Serra |
| author_sort | Vicens Martí |
| collection | DOAJ |
| description | Antiphospholipid syndrome (APS) is an autoimmune coagulation disorder that manifests clinically as venous and arterial thrombosis, and may affect any tissue or organ. Coronary artery involvement, however, is very rare. Case reports in the literature describing patients with coronary acute syndrome and APS treated with coronary angioplasty show conflicting results.We report an adult male patient with APS who presented with an acute myocardial infarction. Given the high risk of thrombosis in these patients, he was treated percutaneously with thrombectomy and abciximab. We review the few cases of coronary angioplasty in patients with APS reported to date. To our knowledge, this is the first case in which acute myocardial infarction due to thrombotic coronary occlusion was treated with thrombectomy and abciximab without stenting the artery. Resumo: A síndrome antifosfolipídica (SAF) é uma doença autoimune da coagulação que se manifesta clinicamente por tromboses venosas e arteriais, podendo afetar qualquer tecido ou órgão. Contudo, o envolvimento das artérias coronárias é extremamente raro. Os casos relatados na literatura de síndrome coronária aguda e de SAF tratados com intervenção coronária percutânea (ICP) apresentam resultados controversos.Relata-se o caso de um doente do sexo masculino com SAF que se apresentou com um enfarte agudo do miocárdio (EAM). Dado o alto risco de trombose nestes doentes, optou-se por ICP com trombectomia e abciximab. Faz-se uma revisão dos poucos casos relatados na literatura de ICP em doentes com SAF. De acordo com a nossa pesquisa, este trata-se do primeiro caso publicado em que um doente com SAF e EAM devido a oclusão coronária trombótica foi tratado com trombectomia e abciximab, sem implantação de stent. Keywords: Antiphospholipid syndrome, Acute coronary syndrome, Thrombectomy, Abciximab, Palavras-chave: Síndrome antifosfolipídica, Síndrome coronária aguda, Trombectomia, Abciximab |
| first_indexed | 2024-12-10T22:13:13Z |
| format | Article |
| id | doaj.art-eea00070635b4f76837e8de69f039819 |
| institution | Directory Open Access Journal |
| issn | 0870-2551 |
| language | English |
| last_indexed | 2024-12-10T22:13:13Z |
| publishDate | 2014-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Revista Portuguesa de Cardiologia |
| spelling | doaj.art-eea00070635b4f76837e8de69f0398192022-12-22T01:31:32ZengElsevierRevista Portuguesa de Cardiologia0870-25512014-07-01337465.e1465.e4Antiphospholipid syndrome and acute myocardial infarction: Treatment with thrombectomy and abciximabVicens Martí0Filipe Seixo1Miguel Santaló2Antonio Serra3Hospital Santa Creu y San Pau, Barcelona, Spain; Corresponding author.Hospital São Bernardo, Centro Hospitalar Setúbal, Setúbal, PortugalHospital Santa Creu y San Pau, Barcelona, SpainHospital Santa Creu y San Pau, Barcelona, SpainAntiphospholipid syndrome (APS) is an autoimmune coagulation disorder that manifests clinically as venous and arterial thrombosis, and may affect any tissue or organ. Coronary artery involvement, however, is very rare. Case reports in the literature describing patients with coronary acute syndrome and APS treated with coronary angioplasty show conflicting results.We report an adult male patient with APS who presented with an acute myocardial infarction. Given the high risk of thrombosis in these patients, he was treated percutaneously with thrombectomy and abciximab. We review the few cases of coronary angioplasty in patients with APS reported to date. To our knowledge, this is the first case in which acute myocardial infarction due to thrombotic coronary occlusion was treated with thrombectomy and abciximab without stenting the artery. Resumo: A síndrome antifosfolipídica (SAF) é uma doença autoimune da coagulação que se manifesta clinicamente por tromboses venosas e arteriais, podendo afetar qualquer tecido ou órgão. Contudo, o envolvimento das artérias coronárias é extremamente raro. Os casos relatados na literatura de síndrome coronária aguda e de SAF tratados com intervenção coronária percutânea (ICP) apresentam resultados controversos.Relata-se o caso de um doente do sexo masculino com SAF que se apresentou com um enfarte agudo do miocárdio (EAM). Dado o alto risco de trombose nestes doentes, optou-se por ICP com trombectomia e abciximab. Faz-se uma revisão dos poucos casos relatados na literatura de ICP em doentes com SAF. De acordo com a nossa pesquisa, este trata-se do primeiro caso publicado em que um doente com SAF e EAM devido a oclusão coronária trombótica foi tratado com trombectomia e abciximab, sem implantação de stent. Keywords: Antiphospholipid syndrome, Acute coronary syndrome, Thrombectomy, Abciximab, Palavras-chave: Síndrome antifosfolipídica, Síndrome coronária aguda, Trombectomia, Abciximabhttp://www.sciencedirect.com/science/article/pii/S0870255114001528 |
| spellingShingle | Vicens Martí Filipe Seixo Miguel Santaló Antonio Serra Antiphospholipid syndrome and acute myocardial infarction: Treatment with thrombectomy and abciximab Revista Portuguesa de Cardiologia |
| title | Antiphospholipid syndrome and acute myocardial infarction: Treatment with thrombectomy and abciximab |
| title_full | Antiphospholipid syndrome and acute myocardial infarction: Treatment with thrombectomy and abciximab |
| title_fullStr | Antiphospholipid syndrome and acute myocardial infarction: Treatment with thrombectomy and abciximab |
| title_full_unstemmed | Antiphospholipid syndrome and acute myocardial infarction: Treatment with thrombectomy and abciximab |
| title_short | Antiphospholipid syndrome and acute myocardial infarction: Treatment with thrombectomy and abciximab |
| title_sort | antiphospholipid syndrome and acute myocardial infarction treatment with thrombectomy and abciximab |
| url | http://www.sciencedirect.com/science/article/pii/S0870255114001528 |
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