Leptin u zhenshchin, bol'nykh sakharnym diabetom2 tipa, ne poluchayushchikh lekarstvennuyusakharosnizhayushchuyu terapiyu
The aim of this study was to investigate the effect of acute hyperinsulinemia to fasting leptin level (fL) secretion and leptin secretion during intravenouse glucose tolerance test (IVGTT). Methods. 32 T2DM women without antidiabetic drugs were studied. Median age of participants was 57,5[50,0;62,5]...
| Format: | Article |
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| Language: | English |
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Endocrinology Research Centre
2010-03-01
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| Series: | Ожирение и метаболизм |
| Subjects: | |
| Online Access: | https://www.omet-endojournals.ru/jour/article/view/5277 |
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| collection | DOAJ |
| description | The aim of this study was to investigate the effect of acute hyperinsulinemia to fasting leptin level (fL) secretion and leptin secretion during intravenouse glucose tolerance test (IVGTT). Methods. 32 T2DM women without antidiabetic drugs were studied. Median age of participants was 57,5[50,0;62,5] years, median body mass index (BMI) was 32,7[29,1;37,1]. Glucose intravenouse bolus solution (40%) was dosing (0,75 g/kg BM). Insulin level was investigated in fasting state (FI), 2 min, 70 min and 120 min after glucose loading. Leptin was investigated in fasting (FL) and 120 min after glucose loading. Results. FL level was 21,1[13,6;39,0] ng/ml. Relationships between FL and HOMA-R, аnd between FL and FI were enough strong (r=0,5, р |
| first_indexed | 2024-03-08T09:14:43Z |
| format | Article |
| id | doaj.art-eea10f08f36f4abe95c1c4707fd41b30 |
| institution | Directory Open Access Journal |
| issn | 2071-8713 2306-5524 |
| language | English |
| last_indexed | 2024-04-24T08:39:30Z |
| publishDate | 2010-03-01 |
| publisher | Endocrinology Research Centre |
| record_format | Article |
| series | Ожирение и метаболизм |
| spelling | doaj.art-eea10f08f36f4abe95c1c4707fd41b302024-04-16T16:16:04ZengEndocrinology Research CentreОжирение и метаболизм2071-87132306-55242010-03-0171414510.14341/2071-8713-52775235Leptin u zhenshchin, bol'nykh sakharnym diabetom2 tipa, ne poluchayushchikh lekarstvennuyusakharosnizhayushchuyu terapiyuThe aim of this study was to investigate the effect of acute hyperinsulinemia to fasting leptin level (fL) secretion and leptin secretion during intravenouse glucose tolerance test (IVGTT). Methods. 32 T2DM women without antidiabetic drugs were studied. Median age of participants was 57,5[50,0;62,5] years, median body mass index (BMI) was 32,7[29,1;37,1]. Glucose intravenouse bolus solution (40%) was dosing (0,75 g/kg BM). Insulin level was investigated in fasting state (FI), 2 min, 70 min and 120 min after glucose loading. Leptin was investigated in fasting (FL) and 120 min after glucose loading. Results. FL level was 21,1[13,6;39,0] ng/ml. Relationships between FL and HOMA-R, аnd between FL and FI were enough strong (r=0,5, рhttps://www.omet-endojournals.ru/jour/article/view/5277type 2 diabetes mellitusleptininsulinivgtt |
| spellingShingle | Leptin u zhenshchin, bol'nykh sakharnym diabetom2 tipa, ne poluchayushchikh lekarstvennuyusakharosnizhayushchuyu terapiyu Ожирение и метаболизм type 2 diabetes mellitus leptin insulin ivgtt |
| title | Leptin u zhenshchin, bol'nykh sakharnym diabetom2 tipa, ne poluchayushchikh lekarstvennuyusakharosnizhayushchuyu terapiyu |
| title_full | Leptin u zhenshchin, bol'nykh sakharnym diabetom2 tipa, ne poluchayushchikh lekarstvennuyusakharosnizhayushchuyu terapiyu |
| title_fullStr | Leptin u zhenshchin, bol'nykh sakharnym diabetom2 tipa, ne poluchayushchikh lekarstvennuyusakharosnizhayushchuyu terapiyu |
| title_full_unstemmed | Leptin u zhenshchin, bol'nykh sakharnym diabetom2 tipa, ne poluchayushchikh lekarstvennuyusakharosnizhayushchuyu terapiyu |
| title_short | Leptin u zhenshchin, bol'nykh sakharnym diabetom2 tipa, ne poluchayushchikh lekarstvennuyusakharosnizhayushchuyu terapiyu |
| title_sort | leptin u zhenshchin bol nykh sakharnym diabetom2 tipa ne poluchayushchikh lekarstvennuyusakharosnizhayushchuyu terapiyu |
| topic | type 2 diabetes mellitus leptin insulin ivgtt |
| url | https://www.omet-endojournals.ru/jour/article/view/5277 |