Ultrastructural Changes and Antitumor Effects of Doxorubicin/Thymoquinone-Loaded CaCO3 Nanoparticles on Breast Cancer Cell Line

Ultrastructural Changes and Antitumor Effects of Doxorubicin/Thymoquinone-Loaded CaCO3 Nanoparticles on Breast Cancer Cell Line

Background: Combination chemotherapy of anticancer drugs is extensively being researched since it could reduce multidrug resistance and side effects as a result of lower dosage of each drug. In this study, we evaluated the effects of doxorubicin-loaded (Dox-ACNP), thymoquinone-loaded (TQ-ACNP) and a...

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Bibliographic Details
Main Authors: Kehinde Muibat Ibiyeye, Norshariza Nordin, Mokrish Ajat, Abu Bakar Zakaria Zuki
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Oncology
Subjects:
doxorubicin
thymoquinone
CaCO3 nanoparticle
breast cancer
combination therapy
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00599/full

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